Hepatitis B is one of the important causes of liver cancer. It is precisely because most infected people do not carry out standard hepatitis B treatment, and do not pay attention to the daily maintenance of liver, which leads to a variety of complications and liver cancer. Therefore, hepatitis B patients must pay attention to the usual treatment and recuperation, to prevent hepatitis B eventually evolved into liver cancer.
01
From second liver to liver cancer, how long does it take?
Hepatitis B virus is a major cause of liver cancer, epidemiologists have also found that hepatitis B epidemic areas are also high incidence of liver cancer. But there are conflicting medical opinions about how long it takes hepatitis B to develop into liver cancer, with data varying slightly by region, ethnicity and other factors.
Overall, about 10% to 30% of chronic hepatitis B cases take five to 10 years to develop into cirrhosis, and another 5% to 10% of cirrhosis takes at least five to 10 years to develop into liver cancer.
From hepatitis B to liver cancer, generally as long as three steps:
Step 1: Hepatitis
When infected with the virus, the body’s immune cells respond, and in the process of clearing the virus, immune damage is caused, leading to the destruction of liver cells, which in turn causes hepatitis. Generally cause liver cancer more, is viral hepatitis, alcoholic hepatitis, steatohepatitis.
Step 2: Cirrhosis
The continuous existence of liver injury and liver inflammation can only achieve scar repair after liver injury, which is manifested as fibrosis. As fibrosis continues to progress, the liver will gradually lose elasticity and become hardened.
Step 3: Liver cancer
After cirrhosis, patients may be accompanied by diabetes, obesity, endocrine disorders, etc., and the abnormal function of the human immune system will lead to weakened tumor monitoring ability, and the immune system cannot remove the mutated liver cells in time, so cancer may occur.
02
Who is the high risk group of liver cancer?
Not all hepatitis will develop into liver cancer, but people with the following factors may have a higher risk of developing liver cancer than the general population, mainly include:
Persons infected with hepatitis B virus/hepatitis C virus;
Chronic alcoholism (alcoholic liver disease);
Patients with non-alcoholic steatohepatitis;
People who consume aflatoxin contaminated food;
People with a family history of liver cancer;
Patients with cirrhosis caused by multiple causes;
Male > 40 years old.
For high-risk groups of liver cancer, regular screening and monitoring should be paid attention to, which is conducive to early detection and treatment of liver cancer, and effectively improve the efficacy of liver cancer. For people at high risk of liver cancer, it is recommended that the starting age of surveillance should be 40 years old.
At present, there are a variety of cutting-edge innovative drugs for hepatitis B, non-alcoholic steatohepatitis, liver fibrosis, cirrhosis and liver cancer. Clinical recruitment is carried out in all parts of China, and free drugs are available. Green access and transportation subsidies are available in public third-class hospitals.
03
A breakthrough has been made in the treatment of liver cancer in China
In terms of the treatment of liver cancer, the treatment of early liver cancer is mostly comprehensive treatment based on surgical resection, which usually adopts local treatment such as surgery, liver transplantation, intervention, ablation and radiotherapy, as well as systematic treatment such as targeted therapy, immunotherapy and chemotherapy.
It is worth mentioning that there is a more effective treatment of liver cancer treatment – yttrium 90 microsphere therapy. It is an advanced technology that can kill liver cancer without an operation, but it is very expensive because the technology is imported from other countries.
In order to break this deadlock, on March 24 this year, yttrium 90 microspheres independently developed in China were applied clinically for the first time, which is also the first time in the world to use “yttrium 90 carbon microspheres” independently developed in China in the treatment of colorectal cancer liver metastasis interventional surgery.
This patient has colorectal cancer liver metastasis, which is very difficult to treat. If traditional treatment is followed, the survival rate is very good, only 10%, and the operation is very difficult. With the yttrium 90 microsphere technique, the treatment was completed in 40 minutes.
According to previous data, the 1-year survival rate of patients with advanced liver cancer using yttrium 90 microspheres is 97%, 3-year survival rate is 86%, and 5-year survival rate can also reach 86%, and the effect is even comparable to that of radical surgical treatment for early liver cancer.
04
Should second liver patient “do not touch wine”?
As we all know, drinking hurts the liver, whether the patient of second liver really have to do completely abstinence?
The study found that the viral load of patients with hepatitis B combined with alcohol was significantly increased, indicating that alcohol can inhibit the immune response of the virus and enhance the carcinogenic effect of the virus. On the other hand, viruses and alcohol can lead to chronic inflammation and cause liver cells to lose control and mutate, so chronic infection of hepatitis B virus and long-term alcohol intake are highly likely to further increase the probability of cirrhosis and liver cancer.
Even if non-hepatitis B patients, everyone is not the same to alcohol metabolism capacity, ethanol into acetaldehyde, stored in the body, itself will involve the liver, so there is no so-called “safe amount of alcohol”, want to protect the liver, the best way is to abstain from alcohol.