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DISEASE INDICATIONS:
Alagille syndrome

MANUFACTURER:
Mirum Pharmaceuticals

USAGE:
Oral

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Livmarli (maralixibat) is an oral solution approved by the U.S. FDA to treat cholestatic pruritus in patients with Alagille syndrome (ALGS) who are 1 year of age or older.

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DISEASE INDICATIONS: Progressive Familial Intrahepatic Cholestasis

MANUFACTURER: Albireo Pharma

USAGE: Oral

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Bylvay is a prescription medication used to treat pruritus in patients aged 3 months and older with progressive familial intrahepatic cholestasis (PFIC), a rare genetic liver disease.

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DISEASE INDICATIONS: Primary Biliary Cholangitis (PBC)

MANUFACTURER: Intercept Pharma Ltd

USAGE: Oral

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Health Canada

Therapeutic Goods Administration (TGA)

Ocaliva is used primarily for treating PBC by binding to the nuclear receptor FXR, modulating liver function and reducing PBC symptoms.