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DISEASE INDICATIONS: Anemia

MANUFACTURER: Astellas Pharma Inc. FibroGen

USAGE: Intravenous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Pharmaceuticals and Medical Devices Agency (PMDA)

Evrenzo (roxadustat) is a medication used to treat anemia in patients with chronic kidney disease (CKD), with a reduction in RBCs and hemoglobin levels.

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MANUFACTURER: Alexion Pharmaceuticals

USAGE: Intravenous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Pharmaceuticals and Medical Devices Agency (PMDA)

Ultomiris (ravulizumab) is a medication used to treat paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), both rare blood disorders that can cause life-threatening complications.

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DISEASE INDICATIONS: Sickle Cell Disease

MANUFACTURER: Novartis

USAGE: Intravenous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Adakveo is a medication used to manage sickle cell disease and reduce the frequency of vaso-occlusive crises in patients 16 and older.

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DISEASE INDICATIONS: Iron deficiency

MANUFACTURER: Shield Therapeutics

USAGE: Oral

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Swissmedic (CH)

Feraccru, also known as Accrufer, is a medication used to treat iron deficiency in adults with or without anemia.

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DISEASE INDICATIONS: Iron deficiency

MANUFACTURER: Shield Therapeutics

USAGE: Oral

MEDICINE APPROVED BY:

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Food and Drug Administration (FDA)

Swissmedic (CH)

Accrufer, also known as ferric maltol, is a prescription medication that supplies the body with iron to treat iron deficiency in adults with or without anemia.

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DISEASE INDICATIONS: Thromboembolism

MANUFACTURER: Alexion Pharmaceuticals

USAGE: Intravenous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Ondexxya (andexanet alfa) is an FDA-approved medication for patients on anticoagulant drugs like rivaroxaban and apixaban who have life-threatening or uncontrolled bleeding.

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DISEASE INDICATIONS: Thromboembolism

MANUFACTURER: Alexion Pharmaceuticals

USAGE: Intravenous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Andexxa is a medication used to treat life-threatening or uncontrolled bleeding in patients taking anticoagulant drugs such as apixaban or rivaroxaban.

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DISEASE INDICATIONS: Acute Hepatic Porphyria (AHP)

MANUFACTURER: Alnylam Pharmaceuticals

USAGE: Subcutaneous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Pharmaceuticals and Medical Devices Agency (PMDA)

Givlaari (givosiran) is a medication used to treat acute hepatic porphyria in adult patients and children over the age of 12.

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Oxbryta (voxelotor) treats sickle cell disease by inhibiting hemoglobin S polymerization and improving blood flow. It is commonly used in adults and children from 12 years of age. The medication is taken orally, once a day, and the recommended starting dose is 1500mg. Side effects may include nausea, headache, and diarrhea, and patients need to be monitored for any changes in hemoglobin levels. Clinical studies have revealed Oxbryta’s efficacy in improving hemoglobin levels, reducing painful crises, and increasing patient quality of life. It is a valuable treatment option for patients with sickle cell disease.