DISEASE INDICATIONS: Risk of cardiovascular events, Hypercholesterolemia

MANUFACTURER: Amgen Inc.

USAGE: Subcutaneous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Health Canada

Pharmaceuticals and Medical Devices Agency (PMDA)

Repatha (evolocumab) is a medication used to lower LDL cholesterol levels. It works by binding to PCSK9 which increases the number of LDL receptors on the liver resulting in a decrease in LDL cholesterol levels. It was approved by the FDA in 2015 and is usually used for patients in high cardiovascular risk or familial hypercholesterolemia.