Monthly Archives: June 2021

When preparing to add complementary foods to children, or add a food that is not eaten, many parents will think of a question: Will the child eat food allergies?

There are grounds for concern. Especially when the child has a history of eczema, rhinitis and so on, every time to add food is careful, see the food containing protein on tenterbones, but sometimes because of nutritional needs and have to eat. What to do in this case? Today we’re going to talk about how to add foods to children that may be at risk for allergies.

No.1

What foods are highly allergenic?

Although allergies can be caused by any food, the eight most common food groups, milk, eggs, soy, wheat, peanuts, wood nuts, fish and shellfish, are classified as highly allergenic.

No.2

Which children are at high risk?

Answering this question requires understanding what an allergic disease is. The most common allergic diseases include atopic dermatitis (eczema), allergic rhinitis, asthma, and food allergies.

Infants and young children are at higher risk of allergic disease if there is a family member with allergic disease. If the child already has an allergic disease, the risk of developing other types of allergic diseases is increased.

To put it simply, infants and young children with a family and personal history of allergic diseases belong to the “high risk group of allergies”; Children with no history of the disease fell into the “standard or low-risk group.”

No.3

Should the addition of highly allergenic foods be postponed?

In 2000 the American academy of pediatrics recommended delaying the introduction of highly allergenic foods. For example, for high-risk groups, milk at age 1; Add eggs at age 2; Peanuts, wood nuts and fish were added at age 3. The recommendation is based on several studies from the late 20th century that suggested that delaying the addition of certain foods might reduce the probability of allergies.

But in 2008, the American Academy of Pediatrics revised its guidelines after more and more in-depth studies came to very different conclusions:

Delaying the addition of highly allergenic foods may not reduce the risk of allergy, but may increase it. Conversely, adding certain foods early on May reduce the risk of allergies to those foods.

The researchers now agree that for “standard or low” risk children, high-allergenic foods can be introduced at any time after 4 to 6 months of age when supplemental foods are added, regardless of age (i.e., 8 months of age is not required for egg yolk consumption). For infants at high risk of allergy, the addition of complementary foods should not be postponed. Highly allergenic solid foods can also be added with caution, but it is recommended to consult an allergist first.

Although milk, eggs, soy, peanuts, wheat, nuts, fish, and shellfish are all allowed to be introduced under the age of 1, the following should be noted:

1. Soybeans, peanuts, nuts and other foods should be processed into appropriate traits to avoid asphyxiation. For example, processing peanuts into peanut butter.
2. Liquid whole milk should be avoided in infants under 1 year of age, not because of allergies, but because it can overload the kidneys and increase the risk of iron deficiency. But don’t limit your intake of milk formula and other dairy products, such as baked goods, cheese, and yogurt, until age 1.
3. It is also generally not recommended to replace breast milk or formula feeding with plant-based milk (e.g., soy milk, walnut milk, almond milk, rice milk, etc.) as it is low in protein and fat and does not meet the nutritional needs of infants.

Non-breast-fed infants who are allergic to cow’s milk protein should consult a dietitian before choosing soy formula if they cannot be relieved by hydrolyzed formula or amino acid formula.

No.4

Before adding highly allergenic foods,

Is an allergy assessment necessary for the child?

Usually not, unless the child meets one of two conditions:

1. The child has a history of severe food allergy;
2. Intractable moderate to severe eczema still exists in the child after the best treatment.

It is advisable for these symptomatic high-risk children to be evaluated by an allergist before adding a highly allergenic food, including a detailed medical history and possibly serum allergen testing and/or skin prick testing.

Most children do not fit into either of these categories and do not require allergy testing before adding highly allergenic foods.

No.5

How to add highly allergenic food?

For all children, when adding highly allergenic foods, it is necessary to follow the principle of adding complementary foods, adding only one new food at a time, starting from a small amount, and observing each new food for 3-5 days.

For “standard or low” risk groups, highly allergenic foods can be introduced at any time after the planned introduction of complementary foods.

For children at high risk, it is more prudent to add highly allergenic foods:

1. Children who have had severe allergic reactions in the past or who still have refractory moderate to severe eczema after treatment should be introduced with highly allergenic foods under the evaluation and guidance of an allergist.
2. If this is not the case, after tolerating some of the less allergenic side foods (such as ferric rice noodles, pureed vegetables), you can initially try these foods at home (rather than in a restaurant or nursery), along with oral antihistamines. If no significant allergic reaction is observed, increase the amount of the food gradually.

No.6

Is it safer to add fewer highly allergenic foods?

It is not recommended to “avoid” these hyperallergenic foods without clinical evidence to limit the variety of foods.

Because protein is diverse and comes from a wide variety of sources, nutrition will be more balanced. Moreover, limiting the variety of complementary foods before age 1 also increases the risk of allergies. If you do not care, you can refer to the following for treatment.

1、 Overview of skin inflammation
Inflammation is what people usually call “inflammation”. It is a kind of defense response of the body to stimulation. It is manifested as redness, swelling, heat, pain and dysfunction. Inflammation can be infectious inflammation caused by infection or non infectious inflammation caused by infection. Skin inflammation is a defense or stress response of the human body to all external stimuli. The external stimulus that causes this defense / stress response is called proinflammatory factor.
2、 The skin is inflamed

1. Acne is the direct manifestation of inflammation, if there is no timely anti-inflammatory, even if the acne is good, it is easy to leave acne imprint.
2. Skin becomes fragile and sensitive, often red, tingling, itching, burning and other symptoms.
3. Accelerate skin aging.
4. The skin turns black.
   3、 Summary of methods to resist skin inflammation
5. Try to avoid skin irritation caused by various factors in the external environment
   Ultraviolet rays in the sun, dust particles in the air and pollen may cause skin irritation and inflammation. Therefore, when going out, we must take protective measures. On the basis of applying sunscreen and isolation, we should always have sunshade, sunshade cap, mouth mask, sunglasses, ice sleeves and other protective tools to prevent skin irritation caused by various external environments.
6. Strive to strengthen skin’s tolerance and defense
   The most important way of anti-inflammatory is to improve the body’s immunity. Daily we should adhere to exercise, and speed up the metabolism through exercise, pay attention to water after exercise.
7. Anti inflammatory and stability maintenance with skin care products
   When inflammation occurs, skin care procedures should be simplified, and daily essence and makeup water can only be used. The essence is concentrated skin care products, which can nourish the skin, relieve inflammation and strengthen the skin.
8. Pay attention to anti inflammation in daily diet
   (1) Diet should pay attention to the balance of fatty acids, fatty acid content of high food: deep sea fish and fish oil.
   (2) Use anti-inflammatory spices: ginger, cinnamon, garlic, black pepper, green tea.
   (3) Stay away from foods that cause inflammation. Inflammatory foods are foods that are high in fat and sugar.
   (4) Polyphenol antioxidants food: dark vegetables are rich in antioxidants, broccoli, tomato, spinach and so on.
   (5) Probiotics: fermented food is rich in probiotics, apple vinegar, yogurt, etc.
   (6) Eating cereals and cereals: can help balance postprandial blood glucose levels.

For two weeks, Chen had not had a good night’s sleep and had been tormented by the word “tumor” in his mind.

Two weeks ago, the unit’s physical examination showed that the tumor markers CEA and CA199 were both elevated, which frightened Chen. “The elevated tumor markers, does that mean the body has a tumor?”

In addition, during those days, Chen did not feel well, his stomach would ache from time to time, and he did not eat properly because of his busy work.

After finishing the work, Chen hurried to the outpatient department of the hospital for consultation, but the doctor comforted her: “Don’t scare yourself young people first, the tumor markers are not necessarily cancer, but also need further examination, I suggest you do a gastroscopy first.”

At the doctor’s suggestion, Chen underwent gastroscopy, and the results showed that there were indeed several polyps in his stomach, but no tumor was found. The polyps were also removed under the microscope at the moment, and only follow-up observation was needed, and there was no serious problem.
Chen was relieved, but at the same time, she wondered: Why pay for a test when tumor markers can’t diagnose cancer?
Check out the result is wrong, is not oneself frighten oneself?

1. What are tumor markers?

Tumor marker (TM) is a kind of substance synthesized by tumor cells or raised in response to tumor cells. Its components mainly include proteins and sugars.
Tumor markers are widely found in cells, tissues, blood or body fluids. They are some indexes of the human body, which can be detected by biochemical and immunological methods, and can reflect the occurrence and development of tumors, or monitor the response of tumors to treatment.

Many people think they have cancer when their tumor markers are elevated during a physical examination, but in fact, there is no tumor marker that can definitively diagnose or rule out a tumor.
For example, in the case of Xiao Chen, her CEA and CA199 were both elevated, but it was not because of cancer, but because of a polyp growing in her stomach.

In fact, in addition to cancer, elevated levels of CEA, or serum carcinoembryonic antigen, can be caused by smoking, ulcerative colitis, pancreatitis, colon polyps, active liver disease, and other conditions.
Although the carbohydrate antigen CA199 is suitable for the diagnosis of pancreatic cancer, the value of CA199 may also be increased due to benign diseases such as acute pancreatitis, biliary stone, cholangitis and non-cancerous liver diseases.

Therefore, it is a great error to judge whether one has cancer simply by increasing the value of tumor markers, and other examination means are needed to be combined for diagnosis.

So, one might ask, why pay for a test when you can’t diagnose cancer?
Isn’t it a waste of money?
In fact, although tumor markers cannot diagnose cancer, they are still an important physical examination item. This is mainly because the clinical testing of tumor markers can be used in the following three ways:

1. It can be used for general examination and screening of tumors to assist in judging whether there is a tumor.
   Early detection and early treatment are the basic principles of tumor treatment.
   Tumor markers are important clues to finding tumors in people at high risk of cancer.
   If the data is abnormal, patients can do other tests according to the actual situation in time to help detect early tumors, timely treatment, and improve the survival rate;
2. After surgery, radiotherapy and chemotherapy for cancer patients, the therapeutic effect can be monitored by tumor markers.
   In general, if the tumor is completely removed and the treatment is good, the number of tumor markers goes down.
3. Dynamic monitoring of tumor markers is helpful to determine whether the tumor has recurred and determine the next treatment plan;
   In addition, the increase or decrease of tumor marker concentration is closely related to tumor prognosis.

Third, the tumor markers corresponding to common cancers should be vigilant when the value is abnormally high

Generally speaking, the tumor markers that are tested by drawing blood in hospitals are mainly for liver cancer, lung cancer, prostate cancer, colorectal cancer and so on.
If abnormal values of the following tumor markers are found, the alert should be raised:

1, liver

Alpha-fetoprotein (AFP) is mainly used in the diagnosis of primary liver cancer, but increased AFP can also be caused by hepatitis, cirrhosis, and pregnancy.
If AFP is more than 400ng/mL and lasts for 4 weeks, pay attention.
If the AFP value is 200~400ng/mL for 8 weeks, it is a relatively dangerous situation, which needs to be further examined in combination with imaging to determine whether the patient has liver cancer.

2, lung cancer,

Cytokeratin 19 fragment (CYFRA21-1) is commonly used to detect lung cancer.
When CYFRA21-1 & gt;
When 30ng/ml, be alert to lung cancer.
In general, the positive detection rate of non-small cell lung cancer is 70%~85%, and the positive rate of carcinoembryonic antigen (CEA) for the diagnosis of lung cancer is about 50%.
In addition, neuron-specific enolase (NSE) may assist in the diagnosis of small cell lung cancer.

Prostate cancer

Prostate specific antigen (PSA) is used to diagnose prostate cancer.
If found PSA>
At 10ng/mL, the risk of prostate cancer is increased and further tests should be done as soon as possible.

4. Colorectal cancer

If the CEA exceeds 20ug/L, it is often indicative of a digestive tract tumor.
In addition, CA199, CA724 and CA242 make up for the deficiency of CEA to a certain extent.

5. Ovarian cancer

Glycosylated antigen 125 (CA125) is used to diagnose ovarian cancer.
If discover the CA125 & gt;
35U/mL, there may be ovarian malignant tumor;
However, when CA125 exceeds >;
70U/mL, it is highly suspected to be due to malignant tumor.

6. Breast cancer

The value of CA15-3 increased, and the sensitivity for early breast cancer was 60%, and the sensitivity for late breast cancer was 80%.
In addition, CEA, CA125 and other tumor markers are complementary indicators for the diagnosis of breast cancer.

Four, in life, in addition to the physical examination, we should also pay attention to the abnormal signals sent by the body

In recent years, the incidence of cancer in China is still on the rise.
Cancer has an incubation period of 10 to 20 years and is not easily detected in its early stages.
In daily life, in addition to regular physical examination, we should also pay attention to abnormal signals sent by the body, such as:

1. Mass appears on the body surface and increases rapidly in a short period of time;

2, warts and moles rapidly increase or rupture;

3. Weight loss for no reason or long-term unexplained fever;

4, often appear nasal obstruction, nasal suction back blood;

5, feel chest discomfort when swallowing, swallowing difficulty or a sense of choking.

6, persistent cough, sputum with blood;

7. Prolonged ulcer or persistent digestive abnormality;

8, urine and feces habits change, blood in urine, blood in stool;

9. Irregular vaginal bleeding occurs in women after the end of menstruation or menopause;
10. Persistent headache, blurred vision and so on.

Five, want to diagnose cancer, still have to carry out what kind of test?

There is no inevitable relationship between tumor markers and cancer. If the value of tumor markers is found to be elevated, other tests, such as ultrasound examination, nuclear magnetic resonance examination and pathological examination, should be performed according to the actual situation in order to diagnose cancer.

As mentioned above, the most important marker for primary liver cancer is AFP.
When the AFP value increases, in order to determine whether there is cancer, ultrasound B-ultrasound examination can be performed to see if there is any tumor, and to check the size and growth site of the tumor.
Second, an MRI examination can be performed to determine the primary lesion.
In addition, if a tumor is found, a biopsy is performed to determine whether the tumor is benign or malignant.

For cancer such as lung cancer, stomach cancer and cervical cancer, chest radiographs, gastroenteroscopy, gynecological examinations and Pap scrapes are required respectively.

Finally, remember the cancer associated with the various tumor markers.
Don’t scare yourself if you find an abnormal number of tumor markers on your checkup.
Generally speaking, people at high risk of cancer, such as those with a family history of cancer, are at higher risk of cancer and need to identify cancer through methods such as ultrasound.
Ordinary people talk to their doctor, and then decide whether to do other tests based on the actual situation.

Introduction: parasitic arthritis is a local disease in developed countries and many developing countries. The clinical manifestations are different. After infection with parasites, some patients have no symptoms, others have many clinical manifestations. The allergic symptoms of the disease include pain, lumps, inflammation of the ear, and arthritis.
Parasite arthritis is a local disease that can cause skeletal deformity

1. This disease is a local disease
   This disease is a local disease, and the patient was not obviously at the beginning. Plasmodium induced arthritis and osteoarthritis are not common in clinic.
2. Can cause bone lesions
   It can cause damage to bone tissue, joints and bone marrow, hinder the normal development of bones, or cause fetal bone deformity. Infection of parasitic bacteria can cause joint damage. Arthritis can be caused by parasites living in muscles around the joint, or by parasites’ metabolites or immune responses.
3. Etiology
   Osteoarthritis caused by parasite infection is very rare in clinic. So far, at least 20 parasites can directly or indirectly destroy human bones and joint systems. It can cause damage to bone tissue, joints and bone marrow, and can also hinder the normal development of bones.
   02
   Parasitic arthritis, in the incubation period, may be asymptomatic for a long time, and may have pain in the limited period
   The disease is divided into four types clinically. Osteococcosis is a disease that causes the disease of small echinococcosis by parasitism of the cercariae in the bone, and its symptoms are painless swelling. The disease is slow, and it is often seen in children.
4. Incubation period
   Larva grows slowly in bone, and has no symptoms for a long time. A few cases may have slight pain.
5. Limitation period
   When the condition worsens, pain, numbness, limp, muscle atrophy of the limbs will occur.
6. Lymphadenopathy can be caused by infection
   Osteoarthritis may occur because of filariasis or Malay. Filariasis can cause lymph nodes to swell. Because of the decrease of resistance, bacteria are easy to invade, causing bacterial infection in local tissues, which may cause peritonitis or peritonitis. In addition, chyloarthritis is also a common disease of filariasis, which can be seen in chylous fluid at the joint, and is common in knee joint.
7. Patients will have limited activity, swelling, pain and fever
   The second is the ankle, which is not affected. It is often unilateral. Generally speaking, it is a benign process, with short duration and no pain and swelling of joints. Sometimes acute, knee joint fluid infiltration, swelling, pain, fever, limited activity, high fever. It can be relieved in 1-2 weeks, and it can be turned into chronic arthritis after recurrence.
   The allergic symptoms of the disease include pain, lumps, inflammation of the ear, arthritis. Among these diseases, osteoarthritis is the most common disease, that is, single joint, especially exposed joints such as wrist and ankle, but pubic Union and rib may occur simultaneously. The symptoms were mainly pain and swelling.
   03
   Parasitic arthritis, diagnosis can be based on the patient’s epidemiology and laboratory results
8. Pathophysiology
   A parasite that invades the skeletal system widely; Echinococcosis in the bone, leading to osteoporosis and echinococcosis
9. Diagnostic methods
   The diagnosis of echinococcosis can be determined by combining epidemiological data, contact history, clinical manifestations, X-ray examination and other auxiliary examinations. The incidence of arthritis in the cauda equina is mainly related to the incidence rate, history of contact, clinical manifestations and X-ray.
10. Laboratory inspection method
    The positive reaction was found in the skin test of hydatid infection (cassony method). Serological tests include hydatid specific antibodies and circulating antigen tests. Indirect hemagglutination test, latex agglutination test, enzyme linked immunosorbent test (ELISA) are all the detection methods. Blood smear examination showed that some patients had filariasis at night. The synovial fluid was examined with cream, sterility and hyperlipidemia.
11. Other inspection methods
    The X-ray examination of filariasis was found in the local periosteum thickening, periostitis and cortex thickening. The degree of destruction of bone cortex is different because of the invasion of periosteum and bone to form new periosteum bone. Lymphangiography showed obstruction of lymph nodes and varices.
    04
    Parasite arthritis needs to be distinguished from chondrosarcoma, and the complications have obvious neurological symptoms
12. Differential diagnosis
    Coccidiosis of bone spinous is a rare disease. It needs to be different from giant cell tumor, fibrocystic osteosarcoma, chondrosarcoma and so on. The spinal focus should be different from tuberculosis and benign tumor. It should be different from rheumatoid arthritis. Need to distinguish from osteoarthritis tuberculosis, rheumatoid arthritis, suppurative arthritis.
13. Complications
    Echinococcosis, spinal cord and sacrum cyst can compress spinal cord or cauda equina nerve, causing obvious nerve symptoms, signs, and even paraplegia. Later stage can lead to secondary chronic suppurative osteomyelitis. When the joint is involved, it can cause pathological dislocation. Filariasis infection with swelling of rubber. Secondary bacterial infection, repeated attacks can cause periostitis or periostitis. The main symptoms of the late stage of arthritis of Dendrolimus punctatus are the disorder of joint function, deformity and rigidity.
14. Treatment
    (1) The treatment of Echinococcus granulosus
    The principle of treatment is to completely remove the diseased bone, but it is unlikely. Scraping and grafting bone is a common method, and albendazole is also a common method.
    (2) Filariasis
    Since the quasi Dirofilaria imitis is a self limiting disease, it is rare in human beings. Filariasis larvae infected with such animals will not develop into adults in human body, but those who cannot develop normally will also be pathogenic. Respiratory tract infection is a common disease in clinic. Sometimes, patients may have joint pain and lower extremity joint self limiting arthritis. The disease is a self limiting disease and does not require special treatment.
    (3) Treatment of Dendrolimus punctatus
    Can use adrenal cortical hormone, anti allergy drug, chlorophenamine, aspirin, etc. These drugs are commonly used in daily life to eliminate inflammation and pain, can be used to protect the function of joints. The long-term fistula, sinus and osteopathy can be treated with sinus resection and debridement. The patients with progressive ankylosis can be treated with joint replacement.
15. Prognosis
    The prognosis depends on the location and scope of involvement. There will be pelvic and spinal lesions, and the prognosis is poor. After treatment, Dendrolimus punctatus rarely recurred, but it is difficult for patients with joint deformity or dysfunction to recover completely.
16. Prevention methods
    The patients were treated comprehensively, the source of infection was removed and the intermediate host was removed. The host should be removed from the epidemic area. The publicity of environmental health in pastoral areas is widely carried out. Good health habits should be developed in early childhood to avoid contact with sick animals.

Good sleep plays a key role in human body. The importance of sleep has been put forward as early as in the “Emperor’s Neijing”.
But modern people, with their fast-paced lifestyles, work and family pressures, are increasingly neglecting the pursuit of good sleep.
Going to bed late and staying up all night is something almost everyone has experienced. More and more people are suffering from sleep disorders, which are painful but still difficult to resolve.
Some people say that vitamin B12 can regulate sleep, is it true?

Adequate and regular sleep is extremely important to a person’s body.

Following the laws of nature, the normal bedtime and sleep time is generally before 10 p.m., but how many people can do that now?
For a large number of people, this time may be just the beginning of the evening life, eating and drinking little is equally unpleasant, psychological satisfaction but the body is increasingly consumed.
Good sleep can help us relieve the tiredness of the day, keep our energy and the food we eat can be better absorbed.

After a whole day’s work and study, our brains will be very tired, and when we have enough sleep, our brains will be much more awake and relaxed.
For minors, a good sleep is also the basis of their physical growth and development.
Usually we will find that after staying up late, the body will be very weak, memory loss, weakened immunity, in the long run, the body will be in a state of sub-health.
If you can’t catch up on sleep during the day, chronic sleep deprivation can take a huge toll on your body and mind.

Some people say that taking vitamin B12 can help insomnia. Many people hear this and take B12 every day, but is this true?
Researchers in Japan have found that taking vitamin B12 can help you sleep, but not because of the vitamin itself.
Many people because of insomnia, become poor appetite, so the body gradually lack of nutrition, taking vitamin B can help the body supplement nutrition, but for people with insomnia, their most critical problem is that the body’s internal system has some disorders, such as endocrine disorders, anxiety and tension.

So what better way can you relieve insomnia?

1. Find out what type of insomnia you have

Many people suffer from insomnia, but not everyone has the same causes and types of insomnia.
From the perspective of traditional Chinese medicine, insomnia is mainly divided into the following types, heart fire, liver qi depression, spleen and stomach imbalance, malnutrition, blood heat.
Each type of person should find the treatment that works best for them.
For example, malnourished people should supplement their own Qi and blood, and work hard on eating, such as jujube and lily are good food materials.
And the heart fire people should go ahead decrease internal heat, this kind of people easily upset irritable temper big, sleep like a fire block in the heart, weekdays can drink rose tea, eat less spicy food.

2. Give your sleep a ritual

Many people nowadays ignore the importance of sleep, not to mention the ritual of sleep.
But sleep is a very important thing in our life, we put a little effort on it, may get a different surprise.
For those who suffer from insomnia, put sleep at the top of your list.
Just before you go to sleep, keep your body on an even keel. Don’t eat too much or go to bed with an empty stomach.
Try not to play with electronic devices before going to bed, and dim the light.
If you can’t fall asleep immediately, listen to soothing music.
Try not to do mental tasks before going to bed. Try not to do exercise before going to bed to get your body excited.
Stick to a period of time to adjust their own schedule, the state of mind put peace, believe that good sleep will find you.

Conclusion: Taking vitamin B12 alone is not a good way to relieve sleep.
We should find out the key root cause of our insomnia, the appropriate medicine.
Take care of your body and give your body more time to rest. I believe you will have better and better changes with enough sleep.

Xiaomeng, after all, failed to usher in the first ray of sunshine in 2020.
This girl in the Department of anesthesia in a medical college in Sichuan Province, in order to celebrate the cross-year celebration on the evening of December 31, 2019, boyfriend Han Mou and she discussed to go to a hospital to steal heptane. It is reported that heptane is an inhaled anesthetic, which will aggravate hypotension and respiratory dysfunction when anesthesia deepens, and can only be used if there is a professional doctor.
Previously, boyfriend Han Mou once used the opportunity of internship in hospital, stole a bottle of heptane and girlfriend Xiao Meng for many times. During the period, Xiao Meng had a respiratory difficulty due to the ingestion of heptane, so he was able to escape from danger after an emergency rescue by Han.
But in that cross night, Meng never woke up again. After being identified by the Western China forensic science identification center of Sichuan Province, the cause of Xiaomeng’s death was in line with the death of heptane poisoning.
Recently, China judicial documents network has published a verdict on the crime of death caused by a fault of Han, who was sentenced to three years’ imprisonment and compensated the family of the dead for more than 83000 yuan.
The hammer. According to visual China
①
And my girlfriend in the rental room and took drugs
Wake up in the morning and find my girlfriend dead
At about 7:30 in the morning, Han was waken up by the alarm clock at the head of the bed. When he woke up, he found his girlfriend Meng had died.
At that time, in the morning of January 1, 2020, Han Mou cried to call his mother: “sorry, something happened.” Han father then called and asked his son what happened. Han told his father on the phone that he and his girlfriend Meng had taken an anesthetic before they went to bed and found their girlfriend dead in the morning.
Han told his father that the drug is not a drug, it is an anesthetic… On the phone, Han father asked his son to call the police.
That morning, after receiving a police call from Han, the police in the district immediately arrived at the scene. Han was detained by police on the same day for stealing heptane, and was detained for criminal detention on January 10, 2020, and arrested on August 5, the same year. After being identified by the Western China forensic science identification center of Sichuan Province, the cause of Xiaomeng’s death was in line with the death of heptane poisoning.
Han and his girlfriend are taking an anesthetic called heptane. It is reported that heptane can cause the dose-related cardiopulmonary function to be low, and the deepening of anesthesia will aggravate the low blood pressure and low respiratory function. It should be used by special calibrated volatiles to accurately control its concentration, and excessive concentration will lead to blood pressure reduction, heart rate slowing down, severe respiratory inhibition and even death. Only personnel trained in the anesthesiology department can use it. Equipment for maintaining airway unobstructed, artificial oxygen, oxygen supply and circulating reproduction must be ready for use at any time.
A few days before the tragedy, Han had just taken the postgraduate examination. Han Mou, born in 1997, is a 2015 grade anesthesiologist in a medical college in Sichuan Province, and his girlfriend, Xiaomeng, is his junior sister. In the eyes of classmates, Han Mou has a good performance in learning. On Christmas night, 2019, Han sent a wechat to his mother, announcing his love with Xiao Meng, and also sent some photos of their lives.
Xiao Meng also studied Anesthesiology, and was a younger sister of Han, who decided their relationship on Christmas Day 2018. Han recalled that before the tragedy, Han mentioned that he was going to Xi’an for a tour with his girlfriend from January 14 to January 17, 2020, when he asked his family what was interesting in Xi’an.
At about 0 on January 1, 2020, in order to meet the new year, Xiao Meng sent a red envelope to his mother; On the other hand, Han also expressed his new year’s wishes to his family in his family group.
Han said that in the early morning of January 1, because of numbness, he and his girlfriend Xiao Meng both took seven x-alkane at the same time, and fell asleep
When Han woke up in the morning, he found his girlfriend Meng had died.
②
Boyfriend stole narcotics from an intern hospital twice
My girlfriend had difficulty breathing because of her ingestion
Han and his girlfriend took the heptane, which Han Mou stole from the hospital where he had been practicing.
According to Han, on December 31, 2019, he and his girlfriend discussed to steal heptane and then take food to celebrate the cross-year. That night, he went to the hospital anesthesia department, where he had previously practiced, and stole two bottles of heptane. It’s not the first time Han stole seven x-alkanes in a hospital, or the first time he and his girlfriend had taken food.
Han said that during June November 2019, he had been an intern in the anesthesia department of the hospital, and he had been exposed to heptane in the operating room and knew where the heptane was stored. Han said that heptane is a volatile drug. During the operation, he was a little bit drunk after passive inhalation. He told his girlfriend Xiaomeng who was learning anesthesia.
“She (girlfriend) also knows heptane, also mentioned that the anesthetist will take these drugs online, and inhale heptane will have a kind of pleasure, like after drinking a little drunk, half asleep, she let me get some back.” Han said that he also wanted that kind of feeling of being drunk, and he did not object.
On a day in mid October 2019, Han took a bottle of seven x alkanes in his internship hospital, and then took food with his girlfriend in a rental house. The next few days, the two took food several times together.
As a student of Anesthesiology Department of Medical College, Han Mou knew the consequences of heptane intake“ In operation, the dosage of narcotic drugs is calculated according to the patient’s weight. Excessive amount will cause respiratory inhibition. If no one is under supervision, it will endanger life and cause respiratory tract occlusion, and thus lead to death. I and Meng both know the harm of narcotic drugs, but out of luck, we want to experience the sense of hunting. In addition, we think that one person sucks, and one person will not be able to see it by the side. ” Han told me that he took three bottles of seven x-alkane twice in the hospital, all of which were taken in the hospital room during the off work time.
In fact, in the process of taking heptane by Han and his girlfriend, there was no danger signal. Han said that once, when his girlfriend little Meng was alone, he looked at her, and found that her girlfriend had shortness of breath and shortness of breath and other difficult breathing conditions after she was inhaled. He immediately gave her first aid. “After that, I told her not to take any more, and threw away the remaining third.”
According to Han, a former anesthesiologist in a hospital, heptane can only be used by the operation personnel, not for sale, special equipment and can not be used by itself, and can only be used if there is a professional doctor.
③
3 years of imprisonment for the crime of death caused by negligence
Compensation for the family members of the victim is more than RMB 83000
Afterwards, the people’s Procuratorate of Shunqing District, Nanchong City, Sichuan Province, charged Han Mou for the crime of death caused by negligence and filed a public prosecution.
According to the law, Han was a student of anesthesia major 2015 in a medical college before the case was committed, and was exposed to inhalation anesthetics heptane during the internship of the Department of anesthesia in the hospital. In mid October 2019, Han stole a bottle of seven x alkane from the hospital anesthetic preparation room, and then took food with his girlfriend Xiaomeng in the rental house several times. During one of the sucking, Xiao Meng had difficulty breathing, and was out of danger after emergency rescue by Han.
After dinner on December 31st, 2019, the two people discussed the theft of heptane for co-feeding, and the defendant Han Mou stole two bottles of heptane from the hospital and took them in their rental room. On January 1, 2020, Han found that Xiao Meng died. After the examination by the physical evidence identification center of the Ministry of public security, heptane and hexafluoroisopropanol were detected from liver tissue, heart blood and urine samples of Xiaomeng, and heptane and hexafluoroisopropanol were detected from a blood sample of Han.
The people’s Court of Shunqing District, Nanchong City, considered that Han, as a student of Anesthesiology Department of Medical College, knew that heptane intake was dangerous and needed to be operated by professionals with special devices. Heptane in the hospital was stolen and taken by the victim Xiaomeng. During the course of ingestion, he failed to pay full attention to the obligation, which resulted in the death of Xiaomeng, The act constitutes the crime of death caused by negligence, and the public prosecution organ charges facts and charges.
In court, Han expressed his willingness to compensate, pleaded guilty and punished, and said he was very sorry now. He deeply realized that the great pain caused by his behavior to the family of small Meng would never be compensated, and that the pain caused by himself and his family also needs to be compensated with his life.
Recently, China judicial document network released the first trial decision of the case. The court sentenced han to three years in prison for the crime of death caused by negligence. The total amount of compensation for the funeral expenses and death compensation of the victim’s family members was more than 83000 yuan.

World Obesity Day

As the global obesity problem is becoming more and more serious, the World Health Organization has identified “obesity” as one of the ten chronic diseases, and the prevention and treatment of obesity has become a major international event.
For this reason, the World Health Organization has designated May 11 as World Obesity Day every year.
The pronunciation of “5·11” is similar to “I want one”, and the final “1” stands for slim, which means “I want to be thin” in colloquial terms.

That’s what we did last time

Have you made a move?

On the eve of World Obesity Day

Learn more about the dangers of obesity

The hazards of obesity

Obesity is often associated with diseases such as dyslipidemia, fatty liver, hypertension, coronary heart disease, abnormal glucose tolerance or diabetes mellitus. It can also be accompanied or complicated with obstructive sleep apnea, gallbladder disease, hyperuricemia and gout, osteoarthropathy, venous thrombosis, impaired reproductive function and some cancers.
Obesity may be a cause and risk factor for these health problems, or may share a common basis with these diseases.

Some researchers have suggested that obesity may even be a risk factor for the severity of novel coronavirus pneumonia, especially in younger patients.
Data from the US and France show that obesity is associated with a higher likelihood of hospital admission and severe illness among COVID-19 patients.

How to lose weight healthily

Intake, consume, both

1. Stop eating and reduce your intake

To overweight fat person, food adjustment should be on the basis of controlling intake of total energy, maintain balanced diet.

In general, it is recommended to reduce energy intake by 300~500 kilocalories a day, strictly control the intake of edible oil and fat, moderate control of white rice noodles and meat, and ensure adequate intake of vegetables, fruits and milk.

Minimum amount of diet

What’s 1200 kilocalories?

3 two staple food

Two lean

One egg

1 cup milk (300 ml)

1 catty vegetables

1 point of oil

Why do you eat like this?
The energy of food mainly comes from the carbohydrate, protein and fat contained in food (these three substances are known as the “three productive nutrients” in nutrition).
Human intake of animal and plant food, digestion and decomposition into these three nutrients, produce a lot of energy.
In addition, dietary fiber, ethanol, organic acids, sugar alcohols can also provide a certain amount of energy for the body.

The level of food energy is related to its own nutritional composition. The more fat the food contains, the higher the converted energy will be. For example, fatty meat has a higher fat content than lean meat, and fried food has a high fat content.
Vegetables and fruits are high in fiber and water, low in fat and protein, and therefore, low in energy.

Move legs, more consumption

Among the four ways of energy consumption, the consumption of physical activity is the only one that can self-regulate energy consumption. With the increase of physical activity, the energy consumption will increase significantly.
So, pay attention to exercise, increase the consumption of physical activity, get rid of excess fat.

“Advice”

Aerobic exercise, to walk fast as the main form, it is recommended that 2 times a day, 30 minutes each time, can be put in lunch and dinner after half an hour, its main points have three: (1) stride: stride is larger than usual walking, walking stride.
② Brisk pace: take 1000-1200 steps every 10 minutes.
③ Long time: walk continuously for 30 minutes per unit.

Resistance training: recommended 1 times a day, 20 minutes each time, with moderate dumbbell exercises, etc., can design their own movements, step by step, according to one’s ability.

Be physically active whenever and wherever possible
Use your commute time

Reduce the amount of driving, car riding and sitting, increase the amount of walking, biking and climbing stairs, and increase the amount of physical activity.

Reduce sedentary time

During the work process, we can stand up and do more activities. We should get up every hour and do stretching exercises or aerobics. We should reduce screen time such as watching TV and playing mobile phones and do more outdoor walking and exercise.

Integrating Sports into Life

Diversified forms of sports combine housework, sports and exercise organically to make life colorful and enjoy sports.

Now most of the middle-aged, there will be the condition of osteoporosis, with the increase of age their bones become more fragile, at this time to pay attention to, the occurrence of this phenomenon is mainly because of young, didn’t take good care of yourself, when you are old, your body will lose a lot of calcium, it has very serious impact on your bones.

However, there are still a lot of people usually pay attention to calcium supplements, in ordinary life, we will eat a lot of food containing oxalic acid, if we eat too much, will also have a certain impact on our body, resulting in the combination of oxalic acid and calcium precipitation, so we usually must pay attention to our eating habits.

Insist on drinking milk every day, 26-year-old woman found osteoporosis

Xiao Zhang is 26 years old.
Although she has just graduated, she is a we-media worker, and her main job is to sit in front of a computer every day, which has led to her particularly serious neck and shoulder disease

Later, her colleague told her in the chat that she might have osteoporosis, so she could try to supplement calcium every day, or insist on drinking milk every day. She followed her colleague’s advice and drank two cups of milk every day, hoping to relieve her condition and improve her health.

Two months later, Xiao Zhang accidentally touched his little toe at home. The pain in his little toe did not get better for a long time. At first, he thought it would get better after a while

But as time went on, the pain got worse and she began to wonder if she had broken a bone. When she went to the hospital, it was discovered that her little finger was indeed broken.

The doctor told Zhang that his bones were extremely loose, which led to today’s results. Zhang told the doctor that he would not drink two glasses of milk every day.
Why would he drink osteoporosis?

After the doctor’s inquiry, the doctor told him that what he drank was not pure milk, but milk drink, which contained a lot of additives and preservatives, and its nutritional value was very low, so it could not play the role of supplemental calcium. The doctor advised Xiao Zhang to drink more pure milk and eat more fruits after returning home.

How can we prevent osteoporosis in our lives?
There are two things you can do

1. A calcium supplement

Osteoporosis is caused by the lack of calcium in the bones. According to this specific situation, we can consciously supplement calcium elements, so that we can timely supplement the lack of calcium in the bones, strong bones, improve bone density.
It also promotes bone growth, making your bones stronger.

2. Keep jogging

Adhere to exercise is the best way to make up calcium, through exercise can effectively promote the absorption and use of calcium, enhance your bone density, prevent osteoporosis, however, in exercise, we must pay attention not to exercise too much, if any, must pay attention to do not bump the situation, otherwise easy to cause fracture.

Osteoporosis, will bring a lot of inconvenience to our body, if you want to improve this situation, you need to listen to the advice of the doctor, in daily life, eat more calcium content of high food, do not blindly take supplements, but also to adjust their mentality, do not have any pressure, take it seriously.

For antibiotic-related diarrhoea, the higher recommended grade is Saccharomyces burrai
In clinical work, we will find that about 5%-39% of the children who take antibiotics have diarrhea, and even diarrhea occurs within 2 weeks after stopping antibiotics. Now, based on the newly released guidelines and clinical cases, I would like to discuss with you: how to choose probiotics to prevent antibiotic-related diarrhea?
Children with XX.
Male;
1 week in November, cough, fever 2 days, 1 week ago without apparent cause cough, dry cough, runny nose, no fever, for the oral azithromycin, lung cough “treatment 3 days, the effect is not good, was hospitalized for two days of fever, the highest temperature is 340 ℃, and chills, with mouth Zhou Qingzi, no diarrhea, again to diagnosis and physical examination:
T39.2℃, P156 beats/min, R 42 beats/min, BP101/67mmHg, SpO 298% (low flow oxygen intake), body weight 9kg, mental fatigue, slightly short breathing, thick breathing sound in both lungs, and fine wet rale can be heard.
Complete examination on admission: blood routine :WBC 24.9×109/L, NE 73.85%, HGB 119g/L, RBC 4.53×1012/L, PLT 337×109/L;
CRP is 131 mg/L.
Chest radiograph shows bronchopneumonia.
The patients were treated with airway patence, anti-infection ceftriaxone (100mg/kg), immunomodulatory globulin, antipyretic, fluid rehydration and other symptomatic supportive treatments.
On the fourth day of treatment, the peak fever of the child decreased, and the reexamination of blood inflammation indexes decreased compared with before, but the number of stool increased to 4 times per day, with diluted stools, no mucus and blood streak, no vomiting, and no obvious abnormality observed in stool routine. The patient was given an oral administration of 250mg Qd with yeast Bragnolla. On the eighth day of treatment, the child was better and discharged from hospital, and stool returned to normal.
Discharge diagnosis: bronchopneumonia;
Antibiotic-related diarrhea.
What is antibiotic associated diarrhea?
Diarrhea and stool frequency that cannot be explained by other causes after antibiotic treatment >
2 times daily for more than 2 consecutive days, excluding other causes, antibiotic associated diarrhea was considered, which is the most common adverse reaction after antibiotic use.
The pathogenesis of antibiotic-associated diarrhea is complex, mainly involving the following four aspects:
1
The intestinal flora is dysregulated
Human gut microbes, restraining each other, for the human body to play defense against infection, immunity, metabolism and nutrition, maintain barrier necessary physiological function, but antibiotics treatment of disease at the same time, sensitive to gut microbes play an inhibitory effect, non sensitive bacteria colonization, lead to intestinal flora imbalance, diarrhea.
2
Contingent pathogen infection
The imbalance of intestinal flora makes conditional pathogens such as Clostridium difficile, Staphylococcus aureus, Klebsiella acidogenes, and Candida albicans directly cause disease. It should be noted that 10%-33% of antibiotic-related diarrhea is caused by Clostridium difficile infection.
3
Intestinal carbohydrate and bile acid metabolism decreased
Antibiotics reduce the bacterial flora in the colon to the fermentation of carbohydrates, unfermented sugars, excess water and sodium, resulting in osmotic diarrhea;
Antibiotics, on the other hand, reduce the number of dehydroxy bacteria, increase the concentration of primary bile acids, promote colonic secretion, and cause secretory diarrhea.
4
Some antibiotics directly stimulate peristalsis in the gut
Antibiotics such as erythromycin, amoxicillin and potassium clavulanate can directly stimulate the intestinal peristalsis to increase, causing diarrhea.
If the children have diarrhea with loose or watery stools, or even mucous stools, pus and blood stools, or flakelike or tubular pseudomemmas, which cannot be explained by various clear causes, the clinical diagnosis can be made: antibiotic-related diarrhea.
Treatment: discontinuation or adjustment of antibiotics, application of probiotics, treatment for specific pathogens in AAD, faecal bacteria transplantation and symptomatic supportive treatment.
Here we will only discuss the use of probiotics.
Antibiotic-related diarrhea, how to choose probiotics?
Intestinal flora dysregulation is the main pathogenesis of antibiotic-associated diarrhea. Therefore, the restoration of normal intestinal flora would theoretically have a therapeutic effect on the disease. However, clinical data on the use of probiotics is extremely limited at present.
Let’s see the following figure, which is the recommendation given by various authoritative indicators or organizations. For antibiotic-related diarrhea, the highest grade is recommended to be yeast Brahler, which is the reason why we chose this case.
In addition to Saccharomycete blahlii, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition Working Group on Probiotics and Probiotics recommends the use of probiotics for the prevention of antibiotic-associated diarrhoea in children.
So, how safe and effective is Saccharomycete Bragnoliae for infants and young children?
All the sensitivity, has published the journal pediatrics, according to a study by January 408-3 years old of children, at the same time of antibiotic treatment, combined with brady’s yeast 250 mg/day, compared with children without using probiotics, added with brady’s yeast group can effectively reduce the incidence of antibiotic associated diarrhea in children with 18.9%, and discontinuation in 2 weeks,
It can also effectively reduce the incidence of antibiotic-related diarrhea by 14% without adverse reactions, and can be used as one of the first choice drugs for the prevention of antibiotic-related diarrhea in infants.
What are the advantages or disadvantages of other bacterial probiotics in the prevention and treatment of antibiotic-associated diarrhea compared to the fungal yeast Brassi?
First, fungi are not afraid of antibiotics, while bacteria are sensitive to certain antibiotics.
For proof, let’s take a look at this study:
This is a foreign study to investigate the susceptibility of common probiotics to commonly used antibiotics (penicillin, cephalosporin, macrolides, quinolones, and fadamycin) in vitro.
The research results are shown in the figure below. The red area represents the probiotics that are sensitive to this antibiotic, while the white area is insensitive. It can be seen that the fungal probiotics are not sensitive to this antibiotic, which is consistent with common sense, while the bacterial probiotics are sensitive to antibiotics to different degrees.
When the combination of probiotics and antibiotics is used for the prevention of antibiotic-related diarrhea, it is necessary to ensure that the probiotics strains used are not sensitive to antibiotics. However, whether the probiotics are consistent with this study in vivo is unknown, and further studies are needed.
With all this said, you may ask, when is the time to prevent antibiotic-related diarrhea?
Probiotics can be used in the prescription of antibiotics when there are the following conditions, and the choice of probiotics is a matter of personal choice:
1, broad-spectrum antibiotics (β-lactams, macrolides, quinolones) and anti-anaerobe antibiotics

2. Antibiotics with high concentration of drugs in feces (erythromycin, clindamycin, cefoperazone) metabolized by liver or excreted by bile
3. Estimated course of antibiotics >
   Eight days
4. Combination of antibiotics
5. Other conditions: premature infants, low birth weight infants, age <
   3 years old, intestinal invasive procedures, a history of antibiotic associated diarrhea, etc.