Description
Sofovir is a medication used for the treatment of chronic hepatitis C infection in adults. The active ingredient in Sofovir is Sofosbuvir. It is manufactured by Hetero Healthcare Ltd. and is available in the form of tablets in a pack of 28 tablets.
Uses:
Sofovir is used in the treatment of chronic hepatitis C infection (HCV genotype 1, 2, 3, or 4) in adults. It works by stopping the virus from reproducing and spreading in the body.
HOW TO USE:
Sofovir should be taken orally as directed by your doctor. The recommended dose is usually one tablet (400mg) daily with or without food. The duration of treatment may vary depending on individual response to treatment.
Storage Conditions:
Sofovir should be stored at room temperature (15°C to 30°C) in a dry place, away from direct sunlight and moisture. Keep the medication out of reach of children and pets.
Mechanism of action:
Sofovir contains Sofosbuvir, which is a nucleotide analog inhibitor. It works by stopping the virus from producing new viruses and multiplying in the body. It blocks the RNA-dependent RNA polymerase (RdRp) enzyme, which the virus needs to replicate.
Precautions:
Sofovir should be used with caution in patients who have a history of severe kidney or liver disease, or who are allergic to Sofosbuvir or any other ingredients in the medication. It should also be used with caution in patients with a history of heart problems or those who are at risk of developing heart problems.
Contraindications:
Sofovir is contraindicated in patients who are allergic to Sofosbuvir or any other inactive ingredients in the medication. It should also not be used in pregnant or breastfeeding women unless prescribed by a doctor.
Drug Interactions:
Sofovir may interact with other medications, such as amiodarone, rifampin, and St. John’s Wort, to affect their efficacy. Inform your doctor about all medications you are currently taking to avoid any interactions.
Overdose:
Overdose of Sofovir can cause severe side effects such as headache, nausea, vomiting, and abdominal pain. Seek immediate medical attention in case of an overdose.
Side Effects:
Common side effects of Sofovir include headache, fatigue, nausea, diarrhea, and insomnia. It may also cause serious side effects such as depression, liver problems, and breathing difficulties. Contact your doctor immediately if you experience any severe side effects while taking Sofovir.
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