Imanib is a medication used in the treatment of certain types of cancer, including chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). It contains the active substance Imatinib and is manufactured by Intas Pharmaceuticals. Imanib tablets are available in a pack of 10 tablets, with each tablet containing 400 mg of Imatinib.
Uses:
– Treatment of chronic myeloid leukemia (CML)
– Treatment of gastrointestinal stromal tumors (GISTs)
– Used as a first-line therapy for CML and as a second-line therapy for GISTs that have failed to respond to other treatments
– Reduces tumor size, prevents further tumor growth, and improves survival rates
How to use:
Imanib is taken orally, usually once a day, with or without food. The recommended dosage and duration of treatment may vary depending on the type of cancer and the patient’s response to therapy. It is crucial to comply with the prescribed dosage and to continue the medication for the duration as directed by a healthcare professional.
Storage Conditions:
Store Imanib in a cool, dry place at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.
Mechanism of action:
Imatinib, the active substance in Imanib, belongs to a class of medications called tyrosine kinase inhibitors. It works by inhibiting the activity of an enzyme called BCR-ABL, which is formed by the fusion of two genes in CML cells. BCR-ABL is responsible for the uncontrolled proliferation and survival of cancer cells, and its inhibition helps to reduce the tumor burden and prevent further tumor growth. Imatinib also inhibits the activity of other tyrosine kinases that are involved in the growth and spread of GISTs. This leads to a reduction in the size of tumors, improved survival rates, and better quality of life for patients.
Precautions:
– Imanib should be used with caution in patients with a history of liver or kidney disease.
– Inform the healthcare provider of all medications being taken, as Imanib can interact with certain drugs.
Contraindications:
– Hypersensitivity to Imatinib or any of the ingredients in the medication
– Use in pregnant women, unless specifically instructed by a healthcare professional
– Use in breastfeeding women, as the safety of Imatinib during breastfeeding has not been established
Drug Interactions:
– Imanib can interact with several medications, including those that affect liver enzymes, anticoagulants, and certain antibiotics. Inform the healthcare provider of all medications being used before starting Imanib.
Overdose:
In case of an overdose, seek emergency medical attention immediately. Symptoms may include nausea, vomiting, diarrhea, abdominal pain, and fluid retention.
Side effects:
– Edema (fluid retention)
– Nausea and vomiting
– Diarrhea
– Abdominal pain or discomfort
– Bleeding or bruising
– Fatigue
– Rash or itching
– Headache
– Muscle cramps or pain
In conclusion, Imanib is a medication used in the treatment of certain types of cancer, including chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). It contains Imatinib and is manufactured by Intas Pharmaceuticals. It is crucial to follow the prescribed dosage and to continue the medication for the duration as directed by a healthcare professional. Imanib is generally well-tolerated, but it can cause some side effects. Regular monitoring of liver function and blood counts is necessary, and caution should be exercised in patients with pre-existing liver or kidney conditions.
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