Description
Clokeran is a chemotherapy medication used in the treatment of certain types of cancer, including chronic lymphocytic leukemia (CLL), Hodgkin’s lymphoma, and non-Hodgkin’s lymphoma. It contains the active substance Chlorambucil and is manufactured by Natco Pharma Ltd. Clokeran tablets are available in a pack of 30 tablets, with each tablet containing 5 mg of Chlorambucil.
Uses:
– Treatment of chronic lymphocytic leukemia (CLL)
– Treatment of Hodgkin’s lymphoma and non-Hodgkin’s lymphoma
– Inhibits the growth and spread of cancer cells, improving overall survival and reducing symptoms associated with cancer
How to use:
Clokeran is taken orally, usually once a day, with or without food. The recommended dosage and duration of treatment may vary depending on the type of cancer and the patient’s response to therapy. It is crucial to comply with the prescribed dosage and to continue the medication for the duration as directed by a healthcare professional.
Storage Conditions:
Store Clokeran in a cool, dry place at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.
Mechanism of action:
Chlorambucil, the active substance in Clokeran, belongs to a class of medications called alkylating agents. It works by interfering with the DNA replication and repair process in cancer cells, thereby disrupting their growth and division. Chlorambucil also suppresses the immune system, which is overactive in some types of cancer and contributes to the spread of cancer cells. This leads to a reduction in the size of tumors, improved survival rates, and better quality of life for patients.
Precautions:
– Clokeran should be used with caution in patients with a history of liver or kidney disease.
– Inform the healthcare provider of all medications being taken, as Clokeran can interact with certain drugs.
Contraindications:
– Hypersensitivity to Chlorambucil or any of the ingredients in the medication
– Use in pregnant women, unless specifically instructed by a healthcare professional
– Use in breastfeeding women, as the safety of Chlorambucil during breastfeeding has not been established
Drug Interactions:
– Clokeran can interact with several medications, including those that affect liver enzymes, anticoagulants, and certain antibiotics. Inform the healthcare provider of all medications being used before starting Clokeran.
Overdose:
In case of an overdose, seek emergency medical attention immediately. Symptoms may include fever, chills, nausea, vomiting, and signs of infection.
Side effects:
– Nausea and vomiting
– Diarrhea
– Hair loss
– Fatigue
– Mouth sores
– Increased risk of infection
– Reduced blood cell counts
– Liver and kidney damage
In conclusion, Clokeran is a chemotherapy medication used in the treatment of certain types of cancer, including chronic lymphocytic leukemia (CLL), Hodgkin’s lymphoma, and non-Hodgkin’s lymphoma. It contains Chlorambucil and is manufactured by Natco Pharma Ltd. It is crucial to follow the prescribed dosage and to continue the medication for the duration as directed by a healthcare professional. Clokeran can cause some side effects, including hair loss, fatigue, and liver and kidney damage. Regular monitoring of liver function and blood counts is necessary, and caution should be exercised in patients with pre-existing liver or kidney conditions.
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