Description
Estram is a brand name for the generic drug Estramustine Phosphate. It is a combination medication consisting of an estrogen derivative and a chemotherapy agent. It is used in the treatment of advanced prostate cancer. It works by interfering with the growth of cancer cells and reducing the production of testosterone.
Uses:
Estram is primarily used in the treatment of advanced prostate cancer, a type of cancer that affects the prostate gland in men. It is used when the cancer has spread to other parts of the body. Estram works by inhibiting the growth of cancer cells and reducing the production of testosterone, which can fuel the growth of prostate cancer cells.
HOW TO USE:
Estram capsules should be taken orally with a full glass of water. It is usually taken three to four times a day with meals. The exact dosage and duration of treatment will depend on the individual’s condition and response to therapy. It is important to follow the instructions provided by the doctor and not exceed the prescribed dose.
Storage Conditions:
Estram capsules should be stored at room temperature, away from moisture and heat. They should be kept out of the reach of children and pets.
Mechanism of Action:
Estram combines the actions of an estrogen derivative and a chemotherapy agent, Estramustine Phosphate. The estrogen component acts by inhibiting the production of testosterone, which is necessary for the growth of prostate cancer cells. The chemotherapy agent component works by interfering with the DNA and protein synthesis in cancer cells, thereby inhibiting their growth and proliferation.
Precautions:
Before taking Estram, it is important to inform your doctor about any allergies or medical conditions you may have. Patients with blood clotting disorders, liver or kidney problems, or a history of heart disease should exercise caution while taking this medication.
Contraindications:
Estram is contraindicated in patients who are allergic to Estramustine Phosphate or any of the ingredients in this medication. It is also contraindicated in women, as it can cause harmful effects on pregnancy or breastfeeding. Additionally, patients with severe liver disease or a history of blood clotting disorders should avoid Estram.
Drug Interactions:
Estram may interact with several other medications, including blood thinners, anticoagulants, and hormonal therapies. It is important to inform your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements.
Overdose:
In case of an overdose of Estram, seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, diarrhea, and blood in the urine.
Side Effects:
The most commonly reported side effects of Estram include nausea, vomiting, diarrhea, and loss of appetite. Other side effects may include fatigue, skin rash, and hot flashes. It may also cause changes in liver function tests and blood count. It is important to report any persistent or severe side effects to your doctor.
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