Zptropin is a synthetic human growth hormone used to treat growth hormone deficiency in children and adults. It comes in a kit that contains 10 vials of 16 IU each and does not include bacteriostatic water.
Composition:
Each vial of Zptropin contains 16 IU of recombinant human growth hormone, which is produced by bacteria using genetic engineering techniques.
Uses:
Zptropin is primarily used to treat growth hormone deficiency. It can also be used to treat short stature in children, Turner syndrome, chronic renal insufficiency, and Prader-Willi syndrome.
HOW TO USE:
Zptropin is injected subcutaneously (under the skin) using an insulin syringe. The injection should be given at bedtime. The site of injection should be rotated to avoid developing lipoatrophy (loss of fat tissue at the injection site).
Dosage:
The recommended dosage for Zptropin depends on the individual’s weight, age, and the condition being treated. The usual dosage range for children is 0.16-0.24 mg/kg/day while the dosage range for adults is 0.15-0.3 mg/day.
Storage Conditions:
Zptropin should be stored in the refrigerator at 2-8°C. Once reconstituted with bacteriostatic water, it can be stored in the refrigerator for up to 14 days.
Mechanism of action:
Zptropin increases the rate of cell division and growth of bone and muscle tissue. It also stimulates the release of insulin-like growth factor-1 (IGF-1) from the liver, which promotes growth in other tissues.
Precautions:
Zptropin should not be used in patients with active cancer, diabetic retinopathy, or severe breathing problems. It should also be used with caution in patients with a history of pancreatitis, liver disease, or kidney disease.
Contraindications:
Zptropin is contraindicated in patients with a known hypersensitivity to the drug or any of the ingredients.
Interactions:
Zptropin may interact with certain medications, such as insulin, glucocorticoids, and thyroid hormone. Patients should inform their doctor of all medications they are taking before starting Zptropin.
Overdose:
Overdose of Zptropin can result in symptoms such as headache, nausea, vomiting, and fluid retention. In severe cases, overdose can cause hypoglycemia (low blood sugar) and adverse effects on the heart and central nervous system.
Side effects:
Common side effects of Zptropin include headache, nausea, vomiting, and injection site reactions. More serious side effects include increased risk of diabetes, intracranial hypertension, and progression of scoliosis. Patients should contact their doctor if they experience any side effects while taking Zptropin.
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