Description
Natdecita is an injectable medication used in the treatment of various types of cancer, including leukemia, lymphoma, and myelodysplastic syndrome (MDS). The active ingredient in Natdecita is Decitabine. It is manufactured by Natco Pharma Limited and is available in the form of an injection in a pack of 1 vial containing 50 mg of the drug.
Uses:
Natdecita is used in the treatment of leukemia, lymphoma, and myelodysplastic syndrome (MDS). It works by inhibiting the growth and spread of cancer cells in the body.
HOW TO USE:
Natdecita should be administered by a healthcare professional through a vein. The recommended dose and administration schedule may vary depending on the type and stage of cancer being treated. Follow the instructions of your doctor carefully before and during treatment.
Storage Conditions:
Natdecita should be stored at room temperature (15°C to 30°C) in a dry place, away from direct sunlight and moisture. Keep the medication out of reach of children and pets.
Mechanism of action:
Natdecita contains Decitabine, which is a DNA methyltransferase inhibitor. It works by blocking the activity of DNA methyltransferase, an enzyme that is involved in the regulation of gene expression. This leads to the reactivation of silenced tumor suppressor genes, which can slow or stop the growth of cancer cells.
Precautions:
Natdecita should be used with caution in patients with liver or kidney disease, or compromised bone marrow function. It should also be used with caution in patients who are pregnant or breastfeeding.
Contraindications:
Natdecita is contraindicated in patients who are allergic to Decitabine or any other inactive ingredients in the medication. It should also not be used in patients with severe liver or kidney disease.
Drug Interactions:
Natdecita may interact with other medications, such as valproic acid and hydroxyurea, to affect their efficacy. Inform your doctor about all medications you are currently taking to avoid any interactions.
Overdose:
Overdose of Natdecita can cause severe side effects such as low blood pressure, bone marrow suppression, and increased risk of infections. Seek immediate medical attention in case of an overdose.
Side Effects:
Common side effects of Natdecita include nausea, vomiting, diarrhea, fatigue, and low blood cell counts. It may also cause severe side effects such as liver toxicity, allergic reactions, and bleeding. Contact your doctor immediately if you experience any severe side effects while taking Natdecita.
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