Fuvestrol is a type of hormone therapy used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is a prescription drug that is administered through injection.
The active ingredient in Fuvestrol is Fulvestrant which is a synthetic estrogen receptor antagonist. Each injection contains 250 mg of fulvestrant.
Fuvestrol is primarily used to treat hormone receptor-positive advanced breast cancer in postmenopausal women who have gone through menopause and have not benefited from other treatments like tamoxifen. It is also used in combination with other drugs to treat breast cancers that have spread to other parts of the body.
Usage and Dosage:
Fuvestrol is given as an injection into the muscle of the buttocks. The usual dose is 500mg administered as two 250mg injections on the same day (one in each buttock), once a month.
Fuvestrol should be stored at room temperature (25°C). Keep the injection in its original packing until its use. Do not freeze or refrigerate it. Do not use the injection if it is expired or tampered with.
Mechanism of Action:
Fulvestrant works by binding to estrogen receptors in the body, thereby blocking the stimulation of cancer cells that require estrogen to grow. It reduces the number of estrogen receptors and degrades existing ones, causing cancer cells to die and resulting in the shrinkage of tumors.
Fuvestrol is contraindicated in patients who are allergic to fulvestrant or any of its ingredients. It should not be given to premenopausal women and women who are pregnant or breastfeeding.
Fulvestrant may interact with other drugs that are metabolized by CYP3A4, and may reduce the efficacy of tamoxifen. It is essential to inform the treating physician about the current medications being taken by the patient to avoid any drug interactions.
Fuvestrol may cause side effects such as pain, redness, or swelling at the site of injection, nausea, vomiting, and headache. It may also cause serious side effects like allergic reactions, liver problems, and blood clotting disorders. The patient must seek emergency medical help in case of any severe side effects.
In conclusion, Fuvestrol: Fulvestrant 250 Mg Injection is an effective hormone therapy used to treat hormone receptor-positive breast cancer in postmenopausal women. It is essential to follow the recommended dosage and storage instructions and take necessary precautions as advised by the physician to avoid any serious side effects.