Virolfi, marketed under the brand name Virolfi, is an antiviral medication used to treat infections caused by cytomegalovirus (CMV) in adults who have received an organ transplant. Virolfi contains Valganciclovir as its active ingredient, which is converted into ganciclovir in the body, inhibiting the replication of CMV.
Composition:
Each Virolfi tablet contains 450mg of Valganciclovir.
Mechanism of Action:
Valganciclovir in Virolfi is a prodrug, which means it is converted into ganciclovir in the body. Ganciclovir works by inhibiting the replication of cytomegalovirus (CMV) by inhibiting its DNA synthesis. CMV can cause serious infections in people with weakened immune systems, such as those who have received an organ transplant.
Uses:
Virolfi is used to treat cytomegalovirus (CMV) infections in adults who have received an organ transplant.
HOW TO USE:
Virolfi should be taken orally with food and plenty of water to reduce the risk of stomach upset. The dosage of Virolfi is dependent on the patient’s weight, kidney function, and the severity of the infection. It is important to take Virolfi exactly as prescribed by your doctor, even if you feel better. Do not stop taking Virolfi without first consulting with your doctor.
Storage Conditions:
Virolfi tablets should be stored at room temperature away from direct sunlight, moisture, and heat. Keep the medication out of reach of children and pets.
Precautions and Contraindications:
Virolfi should not be used in patients with hypersensitivity to valganciclovir, ganciclovir, or any of the ingredients in the medication. Patients with low neutrophil or platelet counts or impaired renal function may need special monitoring while taking Virolfi.
Drug Interactions:
Virolfi may interact with other medications, including didanosine, probenecid, and mycophenolate mofetil. Patients taking these medications should consult with their physician before taking Virolfi.
Overdose:
In case of an overdose, seek emergency medical attention. Symptoms of an overdose may include abdominal pain, nausea, or vomiting.
Side Effects:
Common side effects of Virolfi include diarrhea, nausea, vomiting, and fever. In rare cases, patients may experience severe allergic reactions, such as hives or difficulty breathing. Patients who experience any unusual or severe side effects while taking Virolfi should contact their physician immediately.
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