Zelgor: Abiraterone 250 Mg Tablets 120’s is a medication used to treat advanced prostate cancer in men. The composition of Zelgor contains the active ingredient abiraterone, a selective inhibitor of androgen biosynthesis.
Zelgor is used in combination with prednisone or prednisolone to treat metastatic castration-resistant prostate cancer in adults who have received prior treatment with docetaxel. It is also used in the treatment of newly diagnosed high-risk metastatic castration-sensitive prostate cancer.
Usage and Dosage:
Zelgor is administered orally in the form of tablets. The recommended dose for metastatic castration-resistant prostate cancer is 1000 mg once daily with prednisone 5 mg twice daily. For newly diagnosed metastatic castration-sensitive prostate cancer, the recommended dose is 1000 mg once daily with prednisone 5 mg once daily. The tablets are taken on an empty stomach, either one hour before or two hours after eating.
Zelgor should be stored at room temperature between 15-30°C, protected from light and moisture.
Mechanism of Action:
Zelgor works by blocking an enzyme called CYP17A1, which is involved in the production of androgens (male hormones) in the body. By inhibiting this enzyme, Zelgor reduces the levels of androgens in the body, including testosterone, which can stimulate the growth of prostate cancer cells.
Zelgor should not be used in women who are pregnant or breastfeeding. It should also be avoided in patients with severe liver dysfunction, as abiraterone is metabolized in the liver.
Zelgor may interact with other medications such as strong CYP3A4 inhibitors, which can increase the levels of abiraterone in the body. Therefore, patients should inform their doctor of all medications they are taking or planning to take.
Zelgor may cause several side effects, including fatigue, fluid retention, hypertension, heart problems, liver toxicity, and gastrointestinal symptoms such as nausea, diarrhea, and indigestion. Additionally, it may increase the risk of infections and fractures.
In conclusion, Zelgor: Abiraterone 250 Mg Tablets 120’s is an effective treatment option for advanced prostate cancer in men. However, it should only be used with proper medical supervision and monitored for side effects. Patients should inform their doctors of any pre-existing conditions or medications they are taking before starting Zelgor therapy.