Vesanoid is a medication used to treat a type of leukemia known as acute promyelocytic leukemia (APL) in adults. It contains the active ingredient tretinoin and is available in the form of capsules.
Composition:
Each Vesanoid capsule contains 10 mg of tretinoin as the active ingredient, along with other inactive ingredients like beeswax, butylated hydroxyanisole, hydrogenated soybean oil, and partially hydrogenated vegetable oil.
Uses:
Vesanoid is used to treat acute promyelocytic leukemia (APL) in adults. It works by preventing the growth and development of abnormal cells in the bone marrow, thereby allowing the normal cells to grow and multiply. Vesanoid is typically prescribed in combination with other medications, like chemotherapy.
Usage and Dosage:
The recommended dose of Vesanoid for adults with acute promyelocytic leukemia is typically around 45 mg/m² per day. This dose is typically split into two equal daily doses, taken orally with water. The dosage may be adjusted based on the individual patient’s response to therapy.
Storage Conditions:
Vesanoid should be stored at room temperature between 20°C to 25°C, in its original container, and away from moisture or direct sunlight. This medication should be kept out of reach of children and pets.
Mechanism of Action:
Vesanoid works by binding to specific receptors on the surface of the leukemia cells, inhibiting the growth and development of these abnormal cells. By inhibiting the growth of leukemia cells, Vesanoid allows normal cells to grow and function normally.
Contraindications:
Vesanoid is contraindicated for individuals who are hypersensitive to tretinoin or any of the inactive ingredients in the medication. It is also not recommended for women who are pregnant or breastfeeding.
Side Effects:
The most common side effects of Vesanoid include fatigue, fever, headache, nausea, vomiting, diarrhea, abdominal pain, elevated liver enzymes, and bone pain. Some patients may experience more severe side effects like leukocytosis, hypotension, pulmonary edema, or infertility. Patients should consult their healthcare provider immediately if any concerning symptoms occur.
In conclusion, Vesanoid is a medication used to treat acute promyelocytic leukemia (APL) in adults. The medication works by inhibiting the growth and development of abnormal cells in the bone marrow, allowing normal cells to grow and function normally. Patients should take this medication as prescribed by their healthcare provider, and should consult a healthcare provider immediately if they experience any concerning symptoms. The medication should be stored appropriately and kept out of reach of children and pets.
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