Tilidin 20x 150/12mg is a medication used to manage moderate to severe pain. Each order unit contains 20 tablets of Tilidin with a dosage of 150mg Tilidine hydrochloride and 12mg Naloxone hydrochloride per tablet. It is manufactured by Sandoz, a well-known brand in the pharmaceutical industry.
Each tablet of Tilidin 20x 150/12mg contains 150mg of Tilidine hydrochloride and 12mg of Naloxone hydrochloride.
Tilidin 20x 150/12mg is used to treat moderate to severe pain such as chronic pain or post-surgical pain. It works by binding to specific receptors in the brain and spinal cord, reducing pain perception and increasing pain tolerance. The presence of Naloxone hydrochloride also reduces the risk of misuse or abuse of the medication.
Usage and Dosage:
Tilidin 20x 150/12mg is a prescription medication and should only be taken as directed by a healthcare provider. The recommended adult dosage is one or two tablets every 4-6 hours, not to exceed more than 8 tablets in a day. Patients with liver or kidney disease may require an adjustment in the dosage. The tablet should be taken with a full glass of water and should not be crushed or chewed.
Tilidin 20x 150/12mg should be stored at room temperature between 15°C and 25°C in a cool, dry place away from direct sunlight. It should be kept out of reach of children and pets.
Mechanism of Action:
Tilidine, an opioid agonist, works by binding to specific receptors in the brain and spinal cord, reducing pain perception and increasing pain tolerance. Naloxone hydrochloride, an opioid antagonist, acts as a blocking agent, reducing the risk of misuse or abuse of the medication.
Tilidin 20x 150/12mg should not be taken by patients who are allergic to any of the ingredients or who have a history of drug abuse. It should also not be taken by patients with severe respiratory depression, acute alcoholism, or severe liver or kidney disease. Patients who are taking monoamine oxidase inhibitors (MAOIs) or with severe mental health disorders should also avoid taking this medication.
Tilidin 20x 150/12mg may interact with other medications such as benzodiazepines, sedatives, and antidepressants, which can increase sedation and respiratory depression. Patients should not take this medication with other opioids or central nervous system depressants, such as alcohol, as it can lead to dangerous levels of sedation or respiratory depression.
Common adverse reactions associated with Tilidin 20x 150/12mg include nausea, dizziness, constipation, vomiting, stomach pain, headache, confusion, and dry mouth. In rare cases, patients may experience respiratory depression, allergic reactions, or seizures.
Tilidin 20x 150/12mg is a potent medication used to manage moderate to severe pain. It should be taken only as prescribed by a healthcare provider and with the necessary precautions to avoid any potential adverse reactions. Patients should keep this medication out of reach of children or individuals who may misuse it.