Buy Tasigna : Nilotinib 200 Mg Capsules Online

Tasigna, also known as Nilotinib 200 Mg Capsules, is a medication used for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (CML) in adults. The medication manufactured by Novartis is a tyrosine kinase inhibitor that works by blocking the signals that promote the growth and division of leukemia cells.

Composition:
Tasigna 200 Mg Capsules contain 200mg of nilotinib as an active ingredient.

Uses:
Tasigna 200 Mg Capsules is indicated for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (CML) in adult patients. It is particularly effective against the Bcr-Abl protein, which is responsible for the abnormal proliferation of leukemia cells.

Usage and Dosage:
Tasigna 200 Mg Capsules should be prescribed and administered by a qualified healthcare professional. The medication is taken orally, twice a day, at least one hour before or two hours after eating. The dosage depends on the patient’s CML stage, previous treatment history, and other medical factors. Dose adjustments may be necessary in patients with hepatic or renal impairment.

Storage Conditions:
Tasigna 200 Mg Capsules should be stored at room temperature away from heat, light, and moisture. The medication should be kept in its original container until use, and the container should be tightly closed.

Mechanism of Action:
Tasigna is a selective inhibitor of the Bcr-Abl tyrosine kinase, which is a protein that promotes the growth and proliferation of leukemia cells. By blocking this protein’s activity, Tasigna prevents the uncontrolled division and survival of cancer cells. Tasigna also has activity against other tyrosine kinases, including the platelet-derived growth factor receptor and the c-kit receptor.

Contraindications:
Tasigna is contraindicated in patients with a known hypersensitivity to nilotinib or any of the formulation’s ingredients. It should not be used in patients with hypokalemia, hypomagnesemia, or long QT syndrome. Tasigna should also be avoided in patients with severe hepatic or renal impairment.

Interactions:
Tasigna may interact with several drugs, including strong CYP3A4 inhibitors (such as ketoconazole or clarithromycin) and inducers (such as rifampin or St. John’s wort). The concomitant use of these drugs may increase or decrease Tasigna’s plasma concentration, leading to treatment failure or toxicity.

Side Effects:
The most common side effects of Tasigna 200 Mg Capsules are headache, fatigue, nausea, vomiting, diarrhea, constipation, myalgia, and skin rash. Other possible adverse events include QT prolongation, pancreatitis, and acute hepatic failure. Tasigna is also associated with an increased risk of arterial occlusive events and fluid retention.

In conclusion, Tasigna 200 Mg Capsules is a potent and effective medication used for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia. It must be used with caution and under close medical supervision due to its potential interactions and side effects. The medication’s dose, duration, and administration should be individualized based on each patient’s medical history, concurrent medications, and laboratory values.