Description
Samtica tablets contain Abiraterone acetate as the active ingredient. It is a prescription medicine prescribed by doctors to treat prostate cancer, specifically, metastatic castration-resistant prostate cancer. It is usually given with prednisone to improve its effectiveness. The medication works by hindering the production of androgens, which are male hormones.
Composition:
The active ingredient in Samtica is Abiraterone acetate. It is present in the dosage of 250 mg per tablet. The other inactive ingredients include microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, magnesium stearate, hypromellose, polysorbate 80, iron oxide yellow, and titanium dioxide.
Uses:
Samtica is used to treat metastatic castration-resistant prostate cancer, where the cancer has spread to other body parts, and hormone therapy is no longer working for the patient. It helps to stop the growth of cancer cells and lower the level of male hormones in the body.
Usage and Dosage:
Samtica is an oral medication that is taken once a day. It should be taken on an empty stomach, either one hour before or two hours after a meal, with water. Doctors typically advise taking it at the same time each day, preferably in the morning. Patients are advised to not change, stop, or start the medication dose without consulting their doctor. The standard dosage is one tablet of 250 mg per day.
Storage Conditions:
Samtica tablets need to be stored at room temperature, not exceeding 25°C, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication after the expiry date.
Mechanism of action:
Abiraterone, the active ingredient in Samtica, is an androgen biosynthesis inhibitor. It works by selectively inhibiting CYP17, which is an enzyme responsible for the production of male hormones. This, in turn, lowers the androgen levels in the body, which causes cancer cells to stop growing.
Contraindications:
Samtica is not suitable for everyone. Patients with a history of cardiovascular disease, liver, kidney, or adrenal gland problems, should consult their doctor before taking the medication. Pregnant women should avoid taking Samtica, as it can harm the unborn baby.
Interactions:
Patients taking Samtica should inform their doctor about any other medication that they are taking, including OTC, herbal supplements, and vitamins. Medicines like warfarin, dexamethasone, rifampicin, and phenytoin can interact with Samtica and affect its effectiveness.
Side-Effects:
Like all medicines, Samtica may cause side-effects. Some of the common side-effects include fatigue, joint pain, nausea, vomiting, constipation, hypertension, diarrhea, hot flushes, and headaches. If the side-effects persist, worsen, or become bothersome, patients should immediately consult their doctor. In rare cases, it can cause serious side-effects like high blood pressure, heart problems, and liver damage. It is essential to inform the doctor if you experience any unusual symptoms or side-effects after taking Samtica.
Conclusion:
Samtica (Abiraterone 250mg tablets) is an effective medication to treat metastatic castration-resistant prostate cancer, used alongside prednisone. It reduces the production of male hormones, slows down the growth of cancer cells, and improves the patient’s quality of life. However, it is not suitable for everyone, has some common side-effects, and should be taken as per the doctor’s instructions. Proper storage conditions must be maintained to ensure the medication’s effectiveness.
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