Resof Total is a prescription drug that contains a combination of two antiviral medications – Velpatasvir and Sofosbuvir. It is used to treat chronic hepatitis C viral infections.
Composition:
The active ingredients in Resof Total are Velpatasvir and Sofosbuvir. Velpatasvir is an NS5A inhibitor that prevents viral replication, while Sofosbuvir is an NS5B inhibitor that prevents the hepatitis C virus from multiplying in the body.
Uses:
Resof Total is used to treat chronic hepatitis C viral infections in adults. It is an antiviral medication that works by preventing the virus from multiplying in the body. It is also used in combination with other medications to treat advanced liver disease.
Usage and dosage:
Resof Total is available in tablet form and is taken orally. The recommended dosage for Resof Total is one tablet (100mg Velpatasvir+400mg Sofosbuvir) once a day with or without food. The duration of treatment varies depending on the patient’s medical history and the severity of the infection.
Storage conditions:
Resof Total should be stored in a cool and dry place, away from direct sunlight and heat. It should be kept out of the reach of children. The tablets should be stored in the original container till the time of use.
Mechanism of action:
Resof Total works by inhibiting NS5A and NS5B proteins, which are involved in the hepatitis C viral lifecycle. Velpatasvir and Sofosbuvir work together to stop the virus from reproducing and eventually eliminate it from the body.
Contraindications:
Resof Total is contraindicated in patients with severe liver disease, severe renal impairment, and hypersensitivity to the active ingredients. It should not be used during pregnancy or breastfeeding.
Interactions:
Resof Total may interact with other medications, such as Amiodarone, Carbamazepine, Phenytoin, and Rifampicin. These medications may reduce the effectiveness of Resof Total and can cause adverse reactions. It is essential to inform the doctor about all the medications the patient is taking.
Side effects:
The common side effects of Resof Total include fatigue, headaches, nausea, diarrhea, and insomnia. Serious side effects may include depression, suicidal thoughts, and acute liver failure. It is important to consult a doctor if any adverse reaction is experienced.
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