Buy Kaftrio (elexacaftor/tezacaftor/ivacaftor) Online For Sale
From $11,500.00
Kaftrio is a combination of drugs used to treat cystic fibrosis caused by the F508del mutation in the CFTR gene, which affects the respiratory, digestive, and reproductive systems. It was approved by the FDA in 2019 and improves lung function and reduces chronic respiratory infections by helping the CFTR protein work correctly. Clinical trials have shown up to 14% improvement in forced expiratory volume and reduced sweat chloride levels. Kaftrio has side effects but is generally well-tolerated. It has a high cost, but Vertex Pharmaceuticals is working to ensure access.
Description
Kaftrio is a medication used for the treatment of cystic fibrosis. It is a combination of three drugs: elexacaftor, tezacaftor, and ivacaftor. Kaftrio is designed for use in patients who have a specific genetic mutation called F508del, which is present in around 90% of people with cystic fibrosis.
Cystic fibrosis is a genetic disorder that affects the function of certain organs, primarily the lungs and digestive system. People with cystic fibrosis produce thick, sticky mucus that can clog the airways and interfere with normal breathing. This can lead to chronic lung infections, inflammation, and damage to the lung tissue. In addition, cystic fibrosis can also affect the pancreas, liver, and other organs, causing digestive problems and other complications.
Kaftrio works by helping to correct the underlying genetic defect in cystic fibrosis. Elexacaftor and tezacaftor work together to target a protein called cystic fibrosis transmembrane conductance regulator (CFTR), which is responsible for regulating the movement of salt and water in and out of the cells in the body. In people with cystic fibrosis, this protein is faulty, which leads to the production of thick, sticky mucus. Elexacaftor and tezacaftor help to stabilize the CFTR protein and improve its function, allowing for more effective movement of salt and water in and out of the cells.
Ivacaftor is another drug that is included in the Kaftrio combination. It is designed to help improve the function of the CFTR protein in people with specific genetic mutations that cause cystic fibrosis. Ivacaftor targets a specific mutation called G551D, which can improve overall lung function in people with cystic fibrosis.
Together, these three drugs work in combination to help improve lung function, reduce inflammation, and prevent chronic lung infections in people with cystic fibrosis. Clinical trials have shown that Kaftrio can significantly improve lung function and quality of life in people with cystic fibrosis who have the specific genetic mutation targeted by the drug.
Kaftrio is taken as a pill that is usually taken twice a day with food. It is important to take the medication exactly as prescribed by your doctor and to continue taking it even if you start to feel better. Kaftrio may cause side effects, such as headache, nausea, diarrhea, and stomach pain. If you experience any side effects or have concerns about taking Kaftrio, be sure to discuss them with your doctor.
In conclusion, Kaftrio is a promising new treatment option for people with cystic fibrosis who have a specific genetic mutation called F508del. By targeting the underlying genetic defect in cystic fibrosis, Kaftrio can help to improve lung function, reduce inflammation, and prevent chronic lung infections. If you or a loved one has cystic fibrosis, be sure to discuss with your doctor whether Kaftrio may be a suitable treatment option.
Additional information
| Package | 56 tablets – 75 mg of ivacaftor, 50 mg of tezacaftor and 100 mg of elexacaftor, 56 tablets – 37.5 mg of ivacaftor, 50 mg of tezacaftor and 100 mg of elexacaftor |
|---|
Reviews
There are no reviews yet.