Description
Kabanat 60mg injection is a prescription medicine that contains cabazitaxel as its active ingredient. It is used to treat patients with prostate cancer and has to be administered under medical supervision.
Composition:
Cabazitaxel is a semi-synthetic derivative of taxane, and it binds to the β-subunit of tubulin, inhibiting microtubule depolymerization. It is an antineoplastic agent that helps in preventing the spread of cancer cells in the body.
Uses:
Kabanat 60mg is mainly used to treat patients with metastatic prostate cancer that has not responded to other treatments like docetaxel. It is also used to manage other types of cancers such as breast cancer and non-small cell lung cancer.
Usage and Dosage:
The dosage of Kabanat 60mg injection should be determined by a healthcare professional, as it depends on a patient’s medical condition, weight, and other factors. The medication is administered via intravenous injection over a period of one hour, typically every three weeks. Patients should undergo pre-medication treatment to prevent allergic reactions.
Storage Conditions:
Kabanat should be stored at room temperature and away from excessive heat, humidity, and light. It should be kept out of reach of children and pets.
Mechanism of Action:
Cabazitaxel works by stopping cancer cells from dividing and slowing down their growth. Cancer cells divide rapidly, and cabazitaxel works by binding to microtubules to prevent them from functioning correctly. This process leads to cell division inhibition and ultimately, cancer cell death.
Contraindications:
Kabanat injection is contraindicated in patients who have previously had a hypersensitivity reaction to cabazitaxel, as well as those who are allergic to polysorbate 80. The use of Kabanat is also not recommended for pregnant or nursing women, people with severe liver or kidney disease, and those with a low blood cell count.
Interactions:
Kabanat can interact with other medications, and it is essential to consult with a healthcare professional before taking any other medication. Kabanat should not be used with certain medications, including anti-cancer drugs, ketoconazole, erythromycin, and clarithromycin.
Side Effects:
Kabanat 60mg injection is associated with side effects that may include hair loss, fatigue, nausea, vomiting, diarrhea, constipation, and fever. Other less common side effects include neuropathy, febrile neutropenia, blood clots, and anemia. Immediate medical attention should be sought if severe side effects occur.
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