Intaxel is a prescription medicine that contains the active ingredient Paclitaxel. It is an anti-cancer medication that is used to treat various types of cancers such as breast cancer, ovarian cancer, lung cancer, and others. Intaxel is available in injection form and is manufactured by Fresenius Kabi.
Composition:
Intaxel contains Paclitaxel as the active ingredient, a chemotherapy drug that belongs to a class of medications called taxanes. Paclitaxel works by inhibiting the growth of cancer cells, preventing them from dividing and multiplying.
Uses:
Intaxel is used to treat various types of cancer, including breast cancer, ovarian cancer, non-small cell lung cancer, AIDS-related Kaposi’s sarcoma, and others. It is used alone or in combination with other chemotherapy drugs to slow down or stop the growth of cancer cells.
Usage and Dosage:
Intaxel should be administered only under the supervision of a qualified healthcare professional trained in the use of chemotherapy drugs. The dosage and duration of treatment may vary depending on the type and severity of cancer, as well as the patient’s medical condition and response to the treatment. Intaxel is given as an injection into a vein over several hours, usually once every three weeks.
Storage Conditions:
Intaxel should be stored in a cool, dry place at room temperature (below 25°C) and protected from light. It should be kept out of reach of children and pets.
Mechanism of Action:
Intaxel contains the active ingredient Paclitaxel, which works by inhibiting the growth of cancer cells by preventing their division and multiplication. It does this by binding to microtubules, which are tiny structures consisting of protein fibers that are essential for the formation and maintenance of the cell structure. By binding to microtubules, Paclitaxel prevents them from breaking down, leading to a buildup of stable microtubules that interfere with cell division and growth, ultimately leading to cancer cell death.
Contraindications:
Intaxel is contraindicated in patients with a history of hypersensitivity to Paclitaxel or other ingredients in the formulation. Intaxel should not be used during pregnancy or breastfeeding.
Interactions:
Intaxel may interact with other medicines, including prescription and over-the-counter drugs, vitamins, and herbal supplements. It is important to inform the doctor about all medicines being taken before starting treatment with Intaxel.
Adverse Reactions:
Common side effects of Intaxel include nausea, vomiting, diarrhea, mouth sores, hair loss, fatigue, joint pain, and numbness or tingling in the hands and feet. These symptoms are usually mild and go away after a few days. However, some patients may experience more serious side effects, such as allergic reactions, low blood cell counts, peripheral neuropathy, and others. If any of these occur, patients should seek medical attention immediately.
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