HUTROPIN is a prescription medication containing recombinant human growth hormone (HGH) used to treat growth hormone deficiency in children and adults. The drug is also used to treat cachexia, a condition that causes muscle wasting and weight loss in individuals with chronic illnesses such as HIV and cancer.
HUTROPIN contains 191 amino acid sequences of human growth hormone, which is synthetically produced in a laboratory setting using recombinant DNA technology. It is structurally and functionally similar to the naturally occurring hormone produced by the pituitary gland.
The primary use of HUTROPIN is for the treatment of growth hormone deficiency in both children and adults. It is also used to treat cachexia, a condition that causes muscle wasting and weight loss due to chronic illness.
Usage and Dosage:
The dosage of HUTROPIN depends on the individual’s weight, age, and medical condition. For children, the dose typically ranges from 0.025 milligrams to 0.05 milligrams per kilogram of body weight, administered subcutaneously. For adults, the dose typically ranges from 0.15 milligrams to 0.3 milligrams per day, also administered subcutaneously. The drug should be taken consistently at the same time each day to maintain stable blood levels.
HUTROPIN should be stored refrigerated at a temperature between 2°C to 8°C. When reconstituted, the solution should be kept in a refrigerator and used within 14 days.
Mechanism of Action:
HUTROPIN works by binding to specific receptors on cells in target organs, triggering the release of insulin-like growth factor-1 (IGF-1). This IGF-1 then promotes growth and multiplication of cells, particularly in bones, muscle, and organs. The increased growth and multiplication help to stimulate normal body development and growth.
HUTROPIN is contraindicated in patients with a hypersensitivity to the drug or any of its components. It should not be used in patients who have active malignancy or who are experiencing acute critical illness due to complications like cardiac or respiratory failure.
HUTROPIN may interact with other medications, particularly steroids and glucocorticoids. It may also affect the efficiency of insulin and diabetic medications, necessitating adjustments to the dose of these medications.
The common side effects of HUTROPIN include swelling at the injection site, muscle or joint pain, and headache. Other less common side effects include edema, carpal tunnel syndrome, and gynecomastia (enlarged male breasts). It is essential to monitor blood glucose levels frequently, as the drug can affect insulin sensitivity and cause diabetes-like symptoms.
In conclusion, HUTROPIN is a prescription medication used for the treatment of growth hormone deficiency and cachexia in children and adults. The drug contains synthetic human growth hormone and works by promoting growth and multiplication of cells. HUTROPIN’s dosage varies depending on body weight, age, and medical history. It should be stored at low temperatures, refrigerated, and used within two weeks when reconstituted. As with any medication, adverse effects can occur, so careful monitoring of patients is necessary. Patients should follow the administration instructions as given by their healthcare provider and report any side effects immediately.
100IU, 500IU, 1,000IU