Aprezo (Apremilast) 30 mg Tablets is a medication used in the treatment of certain inflammatory disorders, such as psoriasis and psoriatic arthritis. It contains Apremilast as the active ingredient and is manufactured by Glenmark (Onkos) Pharmaceuticals Ltd. Each tablet contains 30 mg of Apremilast.
Uses:
Aprezo is primarily used for the treatment of moderate to severe plaque psoriasis and active psoriatic arthritis in adults. It works by inhibiting the activity of an enzyme called phosphodiesterase 4 (PDE4), which is involved in the production of inflammatory mediators in the body.
How to Use:
Aprezo should be taken exactly as prescribed by the healthcare provider. The dosage and duration of treatment will depend on individual factors, such as the severity of the condition, response to the medication, and any underlying medical conditions. It is usually taken orally, with or without food, twice daily. It is important to follow the recommended dosage schedule and not to miss any doses.
Storage Conditions:
Aprezo should be stored at room temperature (between 20-25°C) in a dry place, away from direct sunlight and moisture. It should be stored out of the reach of children and pets. Do not use the medication beyond the expiration date.
Mechanism of Action:
Apremilast, the active ingredient in Aprezo, works by inhibiting the activity of phosphodiesterase 4 (PDE4), an enzyme involved in the production of inflammatory mediators in the body. By reducing the production of inflammatory molecules, it helps to improve the symptoms of psoriasis and psoriatic arthritis.
Precautions:
Before taking Aprezo, it is important to inform the healthcare provider about any known allergies, medical conditions, or medications currently being taken. It is also important to follow regular medical check-ups to monitor any potential side effects.
Contraindications:
Aprezo is contraindicated in individuals who are allergic to Apremilast or any other components of the medication. It should not be used by pregnant or breastfeeding women without consulting a healthcare provider.
Drug Interactions:
Aprezo may interact with certain medications, such as rifampin and phenytoin, which may decrease the effectiveness of Aprezo. It is important to inform the healthcare provider about all medications being taken to avoid potential drug interactions.
Overdose:
In case of an overdose of Aprezo, immediate medical attention should be sought. Symptoms of overdose may include gastrointestinal disorders, such as nausea, vomiting, and diarrhea.
Side Effects:
Common side effects of Aprezo include nausea, diarrhea, headache, and weight loss. Other less common side effects may include depression, suicidal thoughts, and decreased appetite. It is important to seek medical advice if any severe or persistent side effects occur.
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