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Imfinzi, a PD-L1 inhibitor medication, is used to treat multiple types of cancer by blocking the PD-L1 protein that allows cancer cells to evade the immune system. Administered every 2-3 weeks by a healthcare professional, clinical trials have shown Imfinzi to be an effective treatment that can lead to longer survival times for patients with advanced bladder and lung cancer. Although there are side-effects, including fatigue and gastrointestinal issues, discussions with a healthcare provider can help determine if Imfinzi is a viable and promising treatment option for patients with certain types of cancers.

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DISEASE INDICATIONS: Breast Cancer, Gynaecological Cancer

MANUFACTURER: AstraZeneca AB

USAGE: Oral

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Health Canada

Therapeutic Goods Administration (TGA)

Medsafe (NZ)

Lynparza is an oral medication used to treat some types of cancer by blocking the action of the PARP enzyme, preventing cancer cells from multiplying. It is used for ovarian, breast, and pancreatic cancer patients with a BRCA gene mutation or triple-negative breast cancer.

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Tecentriq (Atezolizumab) is an immune checkpoint inhibitor used in conjunction with chemotherapy or other cancer medications to attack cancer cells. By blocking PD-L1, a protein on some cancer cells, Tecentriq allows the immune system to recognize and target cancer cells. Clinical trials show that Tecentriq extends survival and improves outcomes in patients with lung cancer, bladder cancer, and triple-negative breast cancer. Tecentriq is generally well-tolerated, administered intravenously once every three or four weeks, and monitored for potential side effects. Tecentriq is FDA-approved for several types of cancer, making it a promising treatment option for many cancer patients.

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Perjeta is a monoclonal antibody used in the treatment of HER2-positive breast cancer. It works by preventing the HER2 receptor from interacting with other receptors. It belongs to the class of drugs known as HER2 inhibitors and is FDA approved to be used in combination with Herceptin and chemotherapy. Perjeta has been shown to significantly improve progression-free survival in patients with metastatic HER2-positive breast cancer. It is administered intravenously once every three weeks and can be continued up to a year or more in certain patients who are responding well to treatment. Common side effects of Perjeta include fatigue, nausea, diarrhea, and hair loss.

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Ibrance (Palbociclib) is a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6) that is used to treat advanced or metastatic breast cancer in postmenopausal women and men. By blocking CDK4/6, Ibrance slows the growth and division of cancer cells, making it effective when used in combination with an aromatase inhibitor or fulvestrant. Side effects may include fatigue, nausea, infections, hair loss, and decreased white blood cell counts, among others. Despite being expensive, most insurance plans cover its cost and manufacturers may offer financial assistance programs. Ibrance may also become a valuable treatment option for other types of cancer in the future.

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Tagrisso (osimertinib) is a targeted cancer therapy designed for treating non-small cell lung cancer (NSCLC) with specific mutations. It works by inhibiting the activity of the EGFR protein that promotes cancer cells’ growth and survival. Clinical trials proved that osimertinib is highly effective in treating advanced NSCLC patients, particularly those with the T790M mutation. A phase 3 trial found that osimertinib was significantly more effective and better-tolerated than chemotherapy at prolonging progression-free survival. Besides, Tagrisso has been studied in combination with other cancer therapies, indicating even better outcomes for advanced NSCLC patients. Its targeted mechanism and high efficacy make it a valuable option for treating this type of cancer.

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Manufacturer:  MSD Pharmaceuticals Pvt Ltd
Composition:  Human Papilloma Virus Vaccine Quadrivalent 0.5ml

Gardasil is an HPV vaccine that protects against cervical cancer, genital warts, and other types of cancer. It is approved for use in both males and females, administered as three injections over six months. The vaccine works by using a protein to stimulate the immune system to produce antibodies to fight the virus. While generally well-tolerated, it doesn’t protect against all types of HPV, so it is important to continue regular screenings. Gardasil is an FDA-approved and CDC-recommended vaccine for individuals between 9 and 45 years old, but a healthcare provider should be consulted to determine if it is the right option for each individual.

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Darzalex (daratumumab) is a monoclonal antibody used to treat multiple myeloma by targeting the CD38 protein on myeloma cells. The drug is approved by the FDA and may be used alone or in combination with other medications. Darzalex is administered intravenously on a weekly or biweekly schedule. Side effects may include infusion-related reactions and respiratory infections. Darzalex should not be used in patients with known hypersensitivity to its components and may not be recommended for use in certain patients. Pregnant and breastfeeding women should avoid Darzalex unless the benefits outweigh the risks.

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Imbruvica (ibrutinib) is a targeted therapy used to treat various types of blood cancers by inhibiting the protein Bruton’s tyrosine kinase (BTK), which allows for the growth and survival of cancer cells. Imbruvica is a long-term therapy prescribed once daily, and patients may continue treatment as long as they respond well. The capsules should be taken orally and are available in different dosages depending on the type of cancer being treated. Side effects may include nausea and bleeding, and patients should inform their doctor of any other medications they are taking to avoid drug interactions. Imbruvica should not be taken if a patient is allergic to the drug or is pregnant or breastfeeding. Patients should seek the guidance of their healthcare provider before taking Imbruvica.