Vocabria (cabotegravir) is a prescription medicine that is used in combination with rilpivirine to treat HIV-1 infected adults. It belongs to a class of antiretroviral drugs called integrase strand transfer inhibitors that work by preventing the replication of the virus inside the body, leading to a reduction in the viral load.
Vocabria is an oral medication that is supplied as a 30-milligram tablet. It is designed to be taken once a day, with or without food. The medication should be used in combination with rilpivirine, which is an oral medication that is supplied as a 25-milligram tablet.
Vocabria works by preventing the activity of an enzyme called integrase, which is essential for the replication of the HIV virus. When integrase is blocked, the virus cannot integrate its DNA into the host cell DNA, which stops it from reproducing. In combination with rilpivirine, Vocabria offers a complete regimen that can suppress the viral load within the individual, preventing HIV-1 from advancing and reaching life-threatening stages.
Vocabria is a relatively new medication, and it was approved for use by the US Food and Drug Administration (FDA) in 2020. Clinical trials have shown that Vocabria is highly effective at suppressing the viral load in HIV-positive individuals, and it is generally well-tolerated with few reported side effects.
Vocabria is not without its risks, however, and patients should discuss their medical history with their doctor before starting the medication. The medication can interact with other medications, and it can cause side effects such as headache, nausea, diarrhea, and rash. In rare cases, Vocabria has also been associated with a severe skin reaction called Stevens-Johnson syndrome.
Overall, Vocabria represents an important advancement in the treatment of HIV-1, offering an effective and convenient new treatment option for patients. However, like all medications, it should only be used under the guidance of a licensed healthcare provider who can monitor its effects on the individual to ensure that it is both safe and effective in treating their HIV-1 infection.
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