Fulvenat (Fulvestrant 250 Mg Injection) is a medication used to treat estrogen receptor-positive breast cancer, which is the most common type of breast cancer in women. The medication is administered by injection into the muscle and works by blocking the estrogen receptor, which is a protein that promotes the growth and spread of breast cancer cells.
Composition:
Each 5 ml injection of Fulvenat contains 250 mg of the active ingredient Fulvestrant. It also includes other inactive ingredients such as benzyl alcohol, castor oil, and para-formaldehyde.
Uses:
Fulvenat is used to treat advanced stages of estrogen receptor-positive breast cancer in women who have gone through menopause and whose cancer has progressed after treatment with other medications. The medication can also be used in combination with other medications for the treatment of breast cancer.
Usage and Dosage:
Fulvenat is administered by a healthcare professional as an injection into the muscle. The standard recommended dose is 500 mg (two injections of 250 mg each) on days 1, 15, and 29, and then once every 4 weeks thereafter. The dosage may be adjusted based on the patient’s response to treatment.
Storage Conditions:
Fulvenat should be stored in a cool, dry place below 25°C, away from direct sunlight. The medication should be kept out of reach of children and pets.
Mechanism of Action:
Fulvestrant, the active ingredient in Fulvenat, works by blocking the estrogen receptor, a protein that promotes the growth and spread of breast cancer cells. The medication helps to slow down the progression of breast cancer by preventing the estrogen receptor from binding to estrogen.
Contraindications:
Fulvenat is contraindicated in patients who are allergic to fulvestrant or any of the other ingredients in the medication. It should not be used in women who have not yet gone through menopause or who have a history of blood clots.
Interactions:
Fulvenat may interact with other medications, including certain antibiotics and antifungals, as well as other medications used to treat breast cancer. Patients should inform their healthcare provider of any medications, vitamins, or supplements they are taking before starting treatment with Fulvenat.
Adverse Reactions:
Common side effects of Fulvenat include injection site reactions, such as pain, redness, or swelling at the injection site. Other side effects may include fatigue, nausea, vomiting, headache, bone pain, and hot flashes. Rare but serious side effects may include allergic reactions, liver problems, and the development of blood clots.
Brand Equivalent:
Fulvenat is the brand name for Fulvestrant 250 Mg Injection, manufactured by Natco Pharma Ltd.
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