Evrenzo (Roxadustat) is a medication used to treat anemia in patients with chronic kidney disease (CKD). Anemia is a common complication in CKD, characterized by a decrease in the number of red blood cells and hemoglobin, which carries oxygen throughout the body. Evrenzo is effective in both dialysis-dependent and non-dialysis dependent patients.
Evrenzo works by stimulating the production of erythropoietin (EPO), a hormone produced by the kidneys that regulates red blood cell production. In patients with CKD, EPO production decreases, leading to anemia. Evrenzo mimics the effects of EPO, stimulating the bone marrow to produce more red blood cells and hemoglobin.
Evrenzo is taken orally, usually once a day, with or without food. The dose is based on the patient’s weight and hemoglobin level. Evrenzo may take several weeks to take effect, and the dose may need to be adjusted based on the patient’s response and any side effects experienced. Common side effects of Evrenzo include nausea, vomiting, and diarrhea. In addition, Evrenzo may increase blood pressure and the risk of blood clots.
Clinical studies have shown the efficacy and safety of Evrenzo in the treatment of anemia associated with CKD. In a study of dialysis-dependent patients, Evrenzo was found to be non-inferior to epoetin alfa, a commonly used medication for anemia in CKD. In addition, Evrenzo was found to be effective in non-dialysis dependent patients, with a significant increase in hemoglobin levels compared to placebo.
Evrenzo represents an important treatment option for patients with anemia associated with CKD. It offers a targeted approach to stimulating red blood cell production and improving hemoglobin levels, potentially improving physical function and quality of life. Healthcare providers should monitor patients closely for any side effects or changes in blood pressure or clotting while taking Evrenzo. In addition, patients should inform their providers of any other medications or supplements they are taking.
In conclusion, Evrenzo is an effective medication used for the treatment of anemia associated with chronic kidney disease, in both dialysis-dependent and non-dialysis dependent patients. By stimulating erythropoietin production, it can improve red blood cell production and hemoglobin levels, potentially improving physical function and quality of life. Although it may cause side effects, healthcare providers can monitor patients closely and make dose adjustments accordingly. For patients with CKD and anemia, Evrenzo represents a new hope for improved symptom management and overall health.




RKim_HeartAndHealth –
Evrenzo has been a vital part of my treatment plan for chronic kidney disease, especially when anemia started affecting my quality of life. I used to feel constantly tired, dizzy, and unable to focus — even small tasks felt overwhelming. Since starting Evrenzo, I’ve seen a steady increase in energy, my color has returned, and my hemoglobin levels are now within the normal range for the first time in years. I feel stronger and more capable, and even my friends and family have noticed the difference. It’s reassuring to have a medication that truly addresses the underlying cause instead of just masking the symptoms. Evrenzo gave me my strength — and my life — back.
Linda Moreno –
Evrenzo has been a steady, reliable treatment for my CKD-related anemia. Before starting it, I was constantly fatigued and found even light chores exhausting. My hemoglobin levels were dangerously low despite dietary adjustments and supplements. Since beginning Evrenzo, my bloodwork has improved significantly — my red blood cell count is up, my hemoglobin is stable, and my overall stamina is much better. I can now manage my daily activities without feeling completely worn out. What I appreciate most is that the medication is well-tolerated, with minimal side effects. It’s made a tangible, positive impact on both my health and confidence.
James Walters –
After struggling for years with anemia caused by chronic kidney disease, Evrenzo has been the first medication that actually made a noticeable difference. Before, I would get lightheaded just from simple tasks, and my energy was non-existent. Within a month of starting Evrenzo, my hemoglobin levels began to rise steadily, and I felt more alert and alive. The fatigue that used to control my days has lessened significantly. My doctor also mentioned that my blood tests look much better than before, showing how well the medication is working. It’s easy to take, gentle on my system, and very effective. I finally feel like I have a bit of my old self back.
SLin_HealthRenewed –
Evrenzo has been a total game-changer in my anemia treatment. I’ve been on several therapies before, but none provided the balance and stability that Roxadustat does. My doctor recommended it as a more convenient option, and it’s been incredibly effective — my blood levels are steady, my color has returned, and I feel more like myself again. The tablets are easy to take, and I’ve had no significant side effects. It’s reassuring to have an oral medication that delivers consistent results without the hassle of injections or hospital visits. I couldn’t be more grateful for this breakthrough.
Michael Turner –
I’ve been taking Evrenzo for several months to help manage anemia caused by chronic kidney disease, and the improvement has been remarkable. My energy levels have gone from sluggish and drained to much more stable throughout the day. I used to need frequent iron supplements and occasional transfusions, but since starting this medication, those have become rare. What I really appreciate is that it’s an oral medication — no more injections! My doctor closely monitors my labs, and everything has remained within a healthy range. Evrenzo has truly made daily life easier and more comfortable.
Randy –
Evrenzo works quickly and reliably for anemia. Smooth IV administration and excellent product quality. Definitely a top choice!
Charlie –
Effective anemia treatment with fast results. Easy intravenous use and great quality from Astellas Pharma. Highly recommend!
Mr. Bravo –
Evrenzo has been a game-changer in managing anemia. Its intravenous administration is straightforward, and I’ve noticed significant improvements in energy and overall well-being. Manufactured by Astellas Pharma and FibroGen, the quality is top-notch. Highly recommended for effective anemia treatment!