Xeljanz is a medication containing Tofacitinib as an active ingredient. It belongs to the class of drugs known as janus kinase inhibitors (JAK inhibitors). It works by blocking certain enzymes responsible for inflammation and immune responses in the body. Xeljanz is used to treat various autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
Uses:
Xeljanz is used to treat various autoimmune diseases such as:
– Rheumatoid arthritis
– Psoriatic arthritis
– Ulcerative colitis
Usage and Dosage:
The recommended dose of Xeljanz is 5 mg twice daily for the treatment of rheumatoid arthritis and psoriatic arthritis. For ulcerative colitis, the recommended dose is 10 mg twice daily for 8 weeks, followed by 5 mg twice daily. The medication should be taken with or without food. Do not crush, break, or chew the tablets. Consult your doctor for the exact dosage and duration of treatment.
Storage Conditions:
Xeljanz should be stored at room temperature, protected from moisture and light. Keep it out of reach of children and pets.
Mechanism of Action:
Xeljanz works by blocking certain enzymes responsible for inflammation and immune responses in the body. It blocks the action of janus kinase enzymes, reducing inflammation and pain associated with autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
Contraindications:
Xeljanz is contraindicated in patients with:
– Hypersensitivity to Tofacitinib or any other ingredients in the medication
– Active infections, including tuberculosis and herpes zoster
– Severe liver or kidney disease
– Pregnancy and lactation
Interactions:
Xeljanz may interact with other medications such as:
– Azathioprine
– Cyclosporine
– Rifampin
– Oral contraceptives
– Warfarin
Consult your doctor before taking any other medications.
Side Effects:
Common side effects of Xeljanz include:
– Headache
– Diarrhea
– Nausea
– Upper respiratory tract infections
– Increased cholesterol levels
Serious side effects include:
– Infections
– Liver damage
– Blood clots
– Malignancies
Consult your doctor if you experience any serious side effects.
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