Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
Introduction
VIGORA-50 is a pharmaceutical product manufactured by German Remedies, known for its efficacy in treating erectile dysfunction (ED) in men. Each tablet contains 50 mg of Sildenafil Citrate, a potent and widely used active ingredient. This medication falls under the category of phosphodiesterase type 5 (PDE5) inhibitors and is renowned for its ability to enhance sexual performance by improving blood flow to the penile region.
Active Ingredient
The active ingredient in VIGORA-50 is Sildenafil Citrate, a selective inhibitor of the enzyme phosphodiesterase type 5 (PDE5). Sildenafil Citrate works by blocking the PDE5 enzyme, which is responsible for the breakdown of cyclic guanosine monophosphate (cGMP). By inhibiting this enzyme, Sildenafil Citrate helps maintain elevated levels of cGMP, which leads to improved vasodilation and increased blood flow to the penis, facilitating an erection in response to sexual stimulation.
Dosage and Administration
Each pack of VIGORA-50 contains 4 tablets, with each tablet containing 50 mg of Sildenafil Citrate. The recommended dosage is one tablet taken orally approximately 30 to 60 minutes before sexual activity. It is essential to swallow the tablet whole with a glass of water. The medication can be taken with or without food. However, consuming a high-fat meal before taking VIGORA-50 may delay its onset of action.
Mechanism of Action
Sildenafil Citrate in VIGORA-50 acts by relaxing the smooth muscles in the blood vessels of the penis, allowing for increased blood flow during sexual arousal. When a man is sexually stimulated, nitric oxide is released in the corpus cavernosum of the penis, leading to the production of cGMP. Sildenafil Citrate inhibits PDE5, the enzyme that breaks down cGMP, thereby prolonging its action and helping to sustain an erection.
Indications
VIGORA-50 is indicated for the treatment of erectile dysfunction (ED), a condition characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It is suitable for men who have difficulty achieving or sustaining an erection during sexual activity. It is important to note that VIGORA-50 does not cure erectile dysfunction or increase sexual desire but helps to facilitate an erection when sexually aroused.
Side Effects
Common side effects of VIGORA-50 include headaches, flushing, indigestion, nasal congestion, and dizziness. These side effects are usually mild and transient. However, if any of these effects persist or become bothersome, it is important to consult a healthcare provider. In rare cases, more severe side effects may occur, such as priapism (a prolonged and painful erection), sudden vision loss, or sudden hearing loss. Immediate medical attention should be sought if any of these severe side effects occur.
Precautions and Warnings
Before taking VIGORA-50, it is crucial to inform your healthcare provider if you have any pre-existing medical conditions, including cardiovascular disorders, high or low blood pressure, liver or kidney problems, or a history of stroke. Patients who are taking nitrate medications or other medications that may interact with Sildenafil Citrate should avoid using VIGORA-50, as this may lead to potentially dangerous drops in blood pressure. Additionally, individuals with a known allergy to Sildenafil Citrate or any other components of the tablet should not use this medication.
Drug Interactions
VIGORA-50 can interact with certain medications, including nitrates (such as nitroglycerin), alpha-blockers, and other PDE5 inhibitors. Combining VIGORA-50 with these drugs can lead to a significant drop in blood pressure. It is important to disclose all medications, including over-the-counter drugs and supplements, to your healthcare provider to avoid potential interactions.
Storage and Handling
VIGORA-50 tablets should be stored in a cool, dry place away from direct sunlight and moisture. The tablets should be kept out of reach of children and pets. Do not use the medication past its expiration date, and ensure that it is stored in its original packaging to maintain its effectiveness.
Conclusion
VIGORA-50 (Sildenafil Citrate Tablets IP) is a highly effective treatment for erectile dysfunction, offering improved sexual performance and confidence. Manufactured by German Remedies, each pack contains 4 tablets of 50 mg Sildenafil Citrate. By following the prescribed dosage and consulting with a healthcare provider, users can experience the benefits of VIGORA-50 while minimizing potential risks and side effects.
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