Description
Grafeel is a brand of injection manufactured by Dr Reddy’s Laboratories. Each prefilled syringe contains 300 mcg of the active ingredient Filgrastim. It is available in a pack of one prefilled syringe and requires a prescription from a qualified healthcare professional.
Uses:
Grafeel is used to stimulate the production of white blood cells in patients who have received chemotherapy or bone marrow transplantation. Filgrastim helps to reduce the risk of infection and improves the body’s ability to fight off bacterial or fungal infections.
How to use:
Grafeel injection should be administered by a healthcare professional. The injection is given under the skin or into a vein. The dosage and duration of treatment depend on the patient’s condition, weight, and response to the medication.
Storage Conditions:
Grafeel injection should be stored in a cool, dry place, away from direct sunlight and heat. It should be kept out of the reach of children and pets.
Mechanism of action:
Filgrastim is a type of synthetic protein that stimulates the production of white blood cells, particularly neutrophils. Neutrophils are important in fighting bacterial and fungal infections. Filgrastim works by binding to specific receptors on bone marrow cells, which increases the production and release of neutrophils into the bloodstream.
Precautions:
Before using Grafeel, it is important to inform your healthcare provider about any existing medical conditions, allergies, or medications you are taking. This medication may cause side effects such as bone pain, headache, and fatigue.
Contraindications:
Grafeel is contraindicated in individuals who are allergic to Filgrastim or any of the other components of the medication. It should not be used by individuals with severe lung or heart problems.
Drug Interactions:
Grafeel can interact with other medications, therefore it is important to inform your healthcare provider about any medications, dietary supplements, or herbal preparations you are taking. Some examples of drugs that can interact with Grafeel include lithium, chemotherapy drugs, and corticosteroids.
Overdose:
In case of an overdose, immediate medical attention should be sought. The symptoms of an overdose may include bone pain, fever, and fatigue.
Side Effects:
Grafeel injection may cause some side effects such as bone pain, headache, and fatigue. In some cases, it may cause severe side effects such as allergic reactions or swelling of the spleen. Patients who experience severe side effects while using Grafeel should seek medical attention immediately.
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